{"id":"W3152869681","doi":"10.24908/iqurcp.10647","title":"8. Genome Guided Discovery of Chlorinated Natural Products in Streptomyces curacoi","year":2018,"lang":"en","type":"article","venue":"Inquiry Queen s Undergraduate Research Conference Proceedings","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Streptomyces; Genome; Natural product; Biology; Gene; Gene cluster; Bacteria; Antibiotics; Computational biology; Genetics; Microbiology; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001734939,0.0002703533,0.0004461629,0.0004127175,0.0001625298,0.000475575,0.000216586,0.0002622163,0.0009810447],"category_scores_gemma":[0.0002076058,0.00009896456,0.0004602166,0.000681676,0.0001394852,0.0001052944,0.0002332779,0.0003322994,0.0004275155],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004676168,"about_ca_system_score_gemma":0.0006982351,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005534842,"about_ca_topic_score_gemma":0.01007485,"domain_scores_codex":[0.9998554,0.00001982079,0.00001064151,0.00002806564,0.0000598877,0.00002625047],"domain_scores_gemma":[0.999886,0.00002145749,0.00002484871,0.000009237361,0.00003467539,0.00002376314],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002601573,0.00007797836,0.001536807,0.0001479301,0.00001074089,0.000369233,0.00005082086,0.0007279534,0.9867568,0.0001749646,0.0002123771,0.009674292],"study_design_scores_gemma":[0.00006050955,0.0008145771,0.02436541,0.00003989221,0.00006890744,0.0007970897,0.0002218622,0.004128975,0.9499648,0.0001383269,0.01937565,0.00002414682],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9752609,0.00310789,0.006155038,0.0004100665,0.00005557313,0.0003111823,0.004952112,0.0003415672,0.009405692],"genre_scores_gemma":[0.9354069,0.003484936,0.03485488,0.0002070818,0.00001526596,0.0001182914,0.01538888,0.00009856956,0.0104252],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005534842,"threshold_uncertainty_score":0.01100522,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09521984261583831,"score_gpt":0.3670983066360162,"score_spread":0.2718784640201779,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}