{"id":"W3153108455","doi":"10.1136/annrheumdis-2021-220202","title":"Primary and secondary non-response: in need of operational definitions in observational studies","year":2021,"lang":"en","type":"editorial","venue":"Annals of the Rheumatic Diseases","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Gilead Sciences; Pfizer; Eli Lilly and Company","keywords":"Medicine; Observational study; Immunogenicity; Biological response modifiers; Secondary care; Intensive care medicine; Primary care; Rheumatoid arthritis; Immunology; Internal medicine; Antibody; Immune system; Family medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.1206122,0.006059526,0.01723731,0.005876231,0.003602776,0.01747156,0.009133013,0.01818958,0.005726683],"category_scores_gemma":[0.3059049,0.002820337,0.005692626,0.004279814,0.00849597,0.0115339,0.002476291,0.04654719,0.00356623],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005405044,"about_ca_system_score_gemma":0.005663492,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001939792,"about_ca_topic_score_gemma":0.00530228,"domain_scores_codex":[0.9439625,0.02366629,0.01599635,0.004136356,0.01125211,0.0009863696],"domain_scores_gemma":[0.4690846,0.4486783,0.01162003,0.008308182,0.05462757,0.007681416],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002890183,0.00004315786,0.0002720169,0.003419959,0.000508277,0.0001405209,0.00009461072,0.00009710259,0.00006164228,0.003008676,0.9768628,0.01520229],"study_design_scores_gemma":[0.001995624,0.0002896571,0.004883558,0.01405638,0.002455386,0.001082705,0.0006857102,0.003002907,0.0003379527,0.0245162,0.9462941,0.0003997256],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"editorial","genre_scores_codex":[0.00005621691,0.01773199,0.0006918983,0.03359509,0.9473692,0.00003716905,0.0001019395,0.00006260926,0.0003539953],"genre_scores_gemma":[0.000974904,0.0104105,0.001246474,0.03884657,0.947045,0.0001001115,0.00007875198,0.0000705733,0.00122717],"genre_candidate":"editorial","genre_consensus":"editorial","teacher_disagreement_score":0.8793878,"threshold_uncertainty_score":0.6378658,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09647775118293042,"score_gpt":0.366254817892422,"score_spread":0.2697770667094915,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}