{"id":"W3153228158","doi":"10.1016/s1470-2045(21)00065-6","title":"Adjuvant pembrolizumab versus placebo in resected stage III melanoma (EORTC 1325-MG/KEYNOTE-054): distant metastasis-free survival results from a double-blind, randomised, controlled, phase 3 trial","year":2021,"lang":"en","type":"article","venue":"The Lancet Oncology","topic":"Cutaneous Melanoma Detection and Management","field":"Medicine","cited_by":389,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"Merck","keywords":"Medicine; Pembrolizumab; Hazard ratio; Internal medicine; Placebo; Clinical endpoint; Population; Oncology; Clinical trial; Melanoma; Surgery; Cancer; Confidence interval; Pathology; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001765476,0.001770678,0.003246107,0.0004228925,0.0003821977,0.0009978594,0.0009527426,0.001670108,0.006175716],"category_scores_gemma":[0.00139562,0.0006761228,0.002097911,0.0003772565,0.001137764,0.001154887,0.0004239828,0.003126938,0.001198044],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008223365,"about_ca_system_score_gemma":0.0008435167,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001482432,"about_ca_topic_score_gemma":0.003014172,"domain_scores_codex":[0.9994553,0.0002824578,0.00003246458,0.0001070708,0.00003223172,0.00009049919],"domain_scores_gemma":[0.9993873,0.0001866853,0.0001516975,0.00004683572,0.00002982838,0.0001977047],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9839202,0.002406549,0.000171043,0.0005272874,0.0006235327,0.00001723394,0.00002962211,0.0001960232,0.001909445,0.0000524294,0.0004601833,0.009686537],"study_design_scores_gemma":[0.9619946,0.03581842,0.001001249,0.00003257221,0.0003660285,0.00001414203,0.00001319226,0.0001995349,0.0001904273,0.00009346048,0.0002663302,0.000009908909],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9829895,0.009104853,0.0007921772,0.000775776,0.000872957,0.002134863,0.0009667049,0.0001652502,0.002197895],"genre_scores_gemma":[0.9842961,0.004257961,0.001302001,0.001163874,0.0005036786,0.002311707,0.0008989298,0.00003355861,0.005232055],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006175716,"threshold_uncertainty_score":0.02065986,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1008113264955529,"score_gpt":0.3732081519797956,"score_spread":0.2723968254842428,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}