{"id":"W3153420496","doi":"10.3390/bioengineering8040049","title":"COVID-19 Diagnostic Strategies. Part I: Nucleic Acid-Based Technologies","year":2021,"lang":"en","type":"review","venue":"Bioengineering","topic":"SARS-CoV-2 detection and testing","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"","keywords":"Pandemic; Coronavirus disease 2019 (COVID-19); Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Outbreak; Diagnostic test; Intensive care medicine; Asymptomatic; Disease; Identification (biology); Asymptomatic carrier; Medicine; Virology; Risk analysis (engineering); Biology; Infectious disease (medical specialty); Pathology; Pediatrics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008175682,0.00122788,0.001031243,0.003573552,0.0002796575,0.001169942,0.0008869544,0.001368496,0.00408968],"category_scores_gemma":[0.0009751762,0.0004610913,0.0007257392,0.002219921,0.0005855391,0.001947189,0.0007918507,0.002143633,0.003122029],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007850212,"about_ca_system_score_gemma":0.001143739,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001086419,"about_ca_topic_score_gemma":0.001249667,"domain_scores_codex":[0.9996454,0.0000543537,0.00005220783,0.00006996494,0.0001396341,0.00003845329],"domain_scores_gemma":[0.9995831,0.0002119459,0.00005788906,0.00001421474,0.0001036156,0.00002925232],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005626074,0.0001080605,0.0001579142,0.01969137,0.00006480997,0.0001595208,0.00007072862,0.0004358854,0.004653321,0.0058706,0.02781267,0.9409189],"study_design_scores_gemma":[0.00001018132,0.0001244067,0.0004871001,0.003050943,0.00005431071,0.0007779261,0.0000435935,0.0001277598,0.001656728,0.001648528,0.991996,0.0000224321],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001450731,0.9970776,0.000309068,0.0002581249,0.000362061,0.00001663851,0.00003490071,0.00001346046,0.001783106],"genre_scores_gemma":[0.0006688196,0.9974518,0.0004005063,0.000264167,0.0001833101,0.00001796863,0.00006998607,0.000002921185,0.0009405632],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00408968,"threshold_uncertainty_score":0.01368135,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09451033032157008,"score_gpt":0.3520004245405611,"score_spread":0.2574900942189911,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}