{"id":"W3153555116","doi":"10.1126/sciadv.abe7006","title":"Comment on “Evidence that the ProPerDP method is inadequate for protein persulfidation detection due to lack of specificity”","year":2021,"lang":"en","type":"article","venue":"Science Advances","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Aging; University of Calgary","funders":"National Cancer Institute; National Institutes of Health; Eidgenössische Technische Hochschule Zürich","keywords":"Computer science; Computational biology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01445221,0.001706772,0.001493339,0.001634307,0.006772364,0.003780974,0.005052267,0.0784122,0.008155758],"category_scores_gemma":[0.06173909,0.001724598,0.002837122,0.0009107461,0.008798288,0.005199676,0.003295109,0.06122854,0.01323885],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.008138985,"about_ca_system_score_gemma":0.007547399,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03749177,"about_ca_topic_score_gemma":0.03368257,"domain_scores_codex":[0.9880052,0.001909805,0.001707025,0.002581753,0.004474424,0.001321802],"domain_scores_gemma":[0.9562739,0.02227439,0.003016571,0.001483737,0.01491612,0.002035233],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007129564,0.0000281307,0.0004421584,0.0001132493,0.00002962751,0.0004851572,0.0002884075,0.00007993122,0.0008440668,0.003210586,0.991193,0.003214307],"study_design_scores_gemma":[0.00009150137,0.00008962278,0.002529727,0.000375133,0.00007413633,0.0005940059,0.0005003914,0.0003083054,0.003145669,0.007167802,0.984959,0.0001647128],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0004936102,0.0008964556,0.000886681,0.9541352,0.04007757,0.00006140744,0.000262968,0.0002473679,0.002938775],"genre_scores_gemma":[0.001390192,0.0002529259,0.0005749338,0.9871011,0.006130862,0.00006108217,0.00002936053,0.00004557051,0.004413993],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.0784122,"threshold_uncertainty_score":0.07643145,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08375623631191477,"score_gpt":0.3740692085398211,"score_spread":0.2903129722279063,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}