{"id":"W3153785318","doi":"10.1016/j.ekir.2021.03.446","title":"POS-423 MAINSTREAMING GENETIC TESTING FOR ADULT NEPHROLOGY: A MODEL FOR A PUBLICLY FUNDED HEALTHCARE SYSTEM FOR AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE AND FOCAL SEGMENTAL GLOMERULOSCLEROSIS","year":2021,"lang":"en","type":"article","venue":"Kidney International Reports","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Medicine; Focal segmental glomerulosclerosis; Genetic testing; Nephrology; Genetic counseling; Intensive care medicine; Autosomal dominant polycystic kidney disease; Health care; Polycystic kidney disease; Internal medicine; Disease; Kidney; Pathology; Bioinformatics; Genetics; Glomerulonephritis; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01198312,0.0003127133,0.0002181324,0.0006071681,0.004141163,0.006901716,0.001802401,0.001911134,0.01634564],"category_scores_gemma":[0.02491813,0.0003461432,0.0006095992,0.0009338075,0.002532423,0.004720582,0.01022125,0.00297568,0.002309517],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.006921744,"about_ca_system_score_gemma":0.03463621,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0133015,"about_ca_topic_score_gemma":0.03098455,"domain_scores_codex":[0.9849563,0.009061052,0.0006642576,0.0009783868,0.00193268,0.002407369],"domain_scores_gemma":[0.96731,0.005600317,0.002977787,0.002866754,0.003809392,0.01743575],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.000924574,0.01232028,0.3415257,0.000480043,0.0001413744,0.003344138,0.0141752,0.0020317,0.005203748,0.0529789,0.1061023,0.4607721],"study_design_scores_gemma":[0.00258081,0.01282587,0.4373265,0.002929927,0.00038721,0.006506227,0.09437476,0.02531629,0.007341293,0.06720599,0.3425869,0.000618323],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6598305,0.000481135,0.0180771,0.2608959,0.00148832,0.001559158,0.0008232823,0.0005955707,0.05624909],"genre_scores_gemma":[0.9391465,0.0003241277,0.02253261,0.02945381,0.0004825661,0.0007363529,0.0003489535,0.0001347394,0.006840288],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01634564,"threshold_uncertainty_score":0.06337357,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01654226047163941,"score_gpt":0.2616335192277066,"score_spread":0.2450912587560671,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}