{"id":"W3153845803","doi":"10.1016/j.joca.2021.02.411","title":"AN IMPROVED METHOD FOR MICRORNA-SEQUENCING ANALYSIS IDENTIFIES A SIGNATURE OF CIRCULATING MICRORNAS IN LATE-STAGE RADIOGRAPHIC KNEE OSTEOARTHRITIS","year":2021,"lang":"en","type":"article","venue":"Osteoarthritis and Cartilage","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Arthritis Society","funders":"","keywords":"microRNA; Biomarker; Deep sequencing; Biomarker discovery; DNA sequencing; Computational biology; Bioinformatics; Osteoarthritis; Biology; Medicine; Genetics; Gene; Proteomics; Pathology; Genome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001447059,0.0009133166,0.001015471,0.001696527,0.0004653716,0.00106592,0.0006353441,0.001539727,0.002005371],"category_scores_gemma":[0.003794375,0.000634594,0.0009277408,0.0008207354,0.0004375106,0.0005533374,0.0006791739,0.001488319,0.001469846],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002620129,"about_ca_system_score_gemma":0.0007301171,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009751753,"about_ca_topic_score_gemma":0.003127633,"domain_scores_codex":[0.9981763,0.0004123572,0.00010927,0.0005872126,0.000557343,0.0001574613],"domain_scores_gemma":[0.9986321,0.0006243283,0.0001505003,0.0001541672,0.0003467509,0.0000921168],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004633724,0.0001085889,0.007167027,0.0002145852,0.000185845,0.0002174363,0.0001146298,0.0006969675,0.9429644,0.0004215836,0.0008728232,0.0465728],"study_design_scores_gemma":[0.0003259435,0.001501958,0.08186416,0.0001036848,0.0007973613,0.006475593,0.0001333884,0.1190945,0.7646508,0.001884661,0.02281481,0.0003531406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.3109095,0.003362173,0.6724979,0.00060068,0.0006425044,0.0008394154,0.00384009,0.003433484,0.003874188],"genre_scores_gemma":[0.2795717,0.0007930428,0.7085981,0.001177343,0.0002101865,0.0008738522,0.003023263,0.000431675,0.005320854],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.002005371,"threshold_uncertainty_score":0.007652938,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0114186742615591,"score_gpt":0.265446255014526,"score_spread":0.2540275807529669,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}