{"id":"W3154757085","doi":"10.1053/j.gastro.2021.03.050","title":"Fecal Microbiota Transplantation for Recurrent Clostridioides difficile Infection Associates With Functional Alterations in Circulating microRNAs","year":2021,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; Island Health; University of Guelph; University of Calgary; University of Alberta","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Crohn's and Colitis Foundation; University of Nottingham; Crohn's and Colitis Foundation of America; Nottingham University Hospitals NHS Trust; Michael Smith Health Research BC; Nottingham Trent University; National Institute of Allergy and Infectious Diseases; Alberta Health Services; National Institute for Health and Care Research; U.S. Department of Veterans Affairs","keywords":"microRNA; Peripheral blood mononuclear cell; Biology; Transplantation; Real-time polymerase chain reaction; Clostridioides; Immunology; Cancer research; Molecular biology; Medicine; Internal medicine; Microbiology; In vitro; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001819102,0.0001842246,0.0003311727,0.0001976181,0.000132854,0.00003687322,0.00003802042,0.0001244764,0.00009792802],"category_scores_gemma":[0.0001099351,0.0001757275,0.0001373936,0.0002478506,0.00006496513,0.00006695429,0.00002187155,0.0003275881,0.000009793416],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002986477,"about_ca_system_score_gemma":0.0001938828,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007195538,"about_ca_topic_score_gemma":0.001522189,"domain_scores_codex":[0.9983982,0.0001158713,0.0003848767,0.0004271355,0.0001844161,0.0004895251],"domain_scores_gemma":[0.9992263,0.000137825,0.00009154328,0.0001604345,0.0002863139,0.00009754338],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.005518444,0.0009772695,0.3311161,0.0002595625,0.0001986037,0.0001742986,0.0002261143,0.0006266629,0.6582342,0.00006014871,0.0007967624,0.001811911],"study_design_scores_gemma":[0.01324356,0.00404715,0.7163797,0.0003953245,0.0003301167,0.002573038,0.0002248996,0.00216416,0.2595089,0.00004185057,0.0008104938,0.0002807496],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933073,0.0001103897,0.003846332,0.00178603,0.0002125366,0.0004887384,0.0001215012,0.00003870819,0.00008849658],"genre_scores_gemma":[0.9969656,0.0001231424,0.0007770441,0.0002246446,0.0002385669,0.0001271457,0.001393493,0.00002590739,0.0001244401],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3987252,"threshold_uncertainty_score":0.7165958,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02525979647949402,"score_gpt":0.2826910079120558,"score_spread":0.2574312114325618,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}