{"id":"W3154828147","doi":"10.15252/emmm.201911754","title":"Myeloid‐resident neuropilin‐1 promotes choroidal neovascularization while mitigating inflammation","year":2021,"lang":"en","type":"article","venue":"EMBO Molecular Medicine","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal; Hôpital Maisonneuve-Rosemont; Université de Montréal","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Natural Sciences and Engineering Research Council of Canada; Foundation Fighting Blindness; Diabetes Canada; Heart and Stroke Foundation of Canada","keywords":"Neuropilin 1; Choroidal neovascularization; Macular degeneration; Angiogenesis; Inflammation; Cancer research; Neovascularization; Myeloid; Immunology; Medicine; Semaphorin; Vascular endothelial growth factor; VEGF receptors; Receptor; Internal medicine; Ophthalmology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002348369,0.0002051077,0.0002147582,0.000048954,0.0001104697,0.00002716119,0.0001427969,0.0001450802,0.0001953297],"category_scores_gemma":[0.0004114031,0.0001928963,0.0001339895,0.0002279762,0.00008866159,0.000007534937,0.0001107724,0.0001002596,0.00001403275],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002102353,"about_ca_system_score_gemma":0.0001350292,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002798613,"about_ca_topic_score_gemma":0.00002268718,"domain_scores_codex":[0.998413,0.0001461893,0.0003482821,0.0004863846,0.000347627,0.0002585518],"domain_scores_gemma":[0.9989803,0.00001214334,0.0001241936,0.0004711455,0.0002970054,0.0001151775],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001264593,0.00001687434,0.001041399,0.00004005109,0.00007819537,0.00006036869,0.0001089891,0.0002547509,0.9917613,0.0002807751,0.0008171209,0.005527501],"study_design_scores_gemma":[0.0007840158,0.0001895151,0.004766294,0.00009759807,0.00007526769,0.00006291272,0.0001399114,0.0003445311,0.9705899,0.0001445684,0.02256906,0.000236408],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9604107,0.007348678,0.02689352,0.002197983,0.0003552612,0.0002501743,0.000005379041,0.0000347679,0.002503504],"genre_scores_gemma":[0.9943391,0.0004458168,0.001205305,0.001140546,0.001251128,0.00004023527,0.0006868746,0.00005295026,0.0008380446],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03392836,"threshold_uncertainty_score":0.7866082,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01003509841020817,"score_gpt":0.2471239255592177,"score_spread":0.2370888271490096,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}