{"id":"W3155124469","doi":"10.1097/01.hjh.0000749236.76139.6d","title":"MMP-2 INHIBITION ATTENUATES HYPERTENSIVE ECCENTRIC CARDIAC HYPERTROPHY AND DYSFUNCTION BY PRESERVING TROPONIN I AND DYSTROPHIN","year":2021,"lang":"en","type":"article","venue":"Journal of Hypertension","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Internal medicine; Left ventricular hypertrophy; Cardiology; Dystrophin; Muscle hypertrophy; Endocrinology; Troponin T; Eccentric; Ejection fraction; Matrix metalloproteinase; Zymography; Blood pressure; Heart failure; Muscular dystrophy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002554828,0.0001951354,0.000754866,0.0001711044,0.0001558112,0.00006674391,0.00002394854,0.0001244931,0.00001203231],"category_scores_gemma":[0.0002967074,0.0001425633,0.0002309841,0.0002021314,0.00006042475,0.0002563093,0.00007998426,0.0003520876,0.000002237247],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006988064,"about_ca_system_score_gemma":0.0000829147,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002777765,"about_ca_topic_score_gemma":5.012774e-7,"domain_scores_codex":[0.998482,0.0001096353,0.0004851332,0.0002742559,0.0004229703,0.0002259901],"domain_scores_gemma":[0.9982937,0.0001027004,0.0002301471,0.000169974,0.0009702827,0.0002331802],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003393674,0.00009269497,0.005466505,0.00009044204,0.0001599023,0.0004524059,0.00006083787,0.00003389456,0.9777584,0.000008105163,0.0100217,0.005515717],"study_design_scores_gemma":[0.02587803,0.005313974,0.3336917,0.005835521,0.007425485,0.1048555,0.006744703,0.02920235,0.4473907,0.000648983,0.03124939,0.001763612],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9640811,0.03158694,0.0001561942,0.003441104,0.0005180633,0.0001282988,0.000008192567,0.00001459743,0.00006548663],"genre_scores_gemma":[0.9896673,0.007240009,0.001778258,0.0006221978,0.0005027325,0.000001089183,0.000023412,0.00003281017,0.0001321869],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5303677,"threshold_uncertainty_score":0.5813562,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01504316216709191,"score_gpt":0.2158449487217779,"score_spread":0.2008017865546859,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}