{"id":"W3155124469","doi":"10.1097/01.hjh.0000749236.76139.6d","title":"MMP-2 INHIBITION ATTENUATES HYPERTENSIVE ECCENTRIC CARDIAC HYPERTROPHY AND DYSFUNCTION BY PRESERVING TROPONIN I AND DYSTROPHIN","year":2021,"lang":"en","type":"article","venue":"Journal of Hypertension","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Internal medicine; Left ventricular hypertrophy; Cardiology; Dystrophin; Muscle hypertrophy; Endocrinology; Troponin T; Eccentric; Ejection fraction; Matrix metalloproteinase; Zymography; Blood pressure; Heart failure; Muscular dystrophy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001795002,0.000727998,0.0005721437,0.0002955443,0.0001730915,0.0002936182,0.0002523368,0.0003408102,0.001629856],"category_scores_gemma":[0.0001183995,0.0001496685,0.0003014015,0.0001227444,0.0002378976,0.00026386,0.0001874659,0.0007703629,0.0003372607],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001685685,"about_ca_system_score_gemma":0.0002858074,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003234013,"about_ca_topic_score_gemma":0.0007974218,"domain_scores_codex":[0.9998642,0.00001136185,0.0000150626,0.00003018068,0.00003068919,0.0000485936],"domain_scores_gemma":[0.9998215,0.00001165589,0.00007238072,0.00001456744,0.00001764009,0.00006232139],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001437627,0.0004172025,0.0003485694,0.0001423733,0.00001711796,0.00006423015,0.00001939348,0.00005366374,0.9946502,0.00004558271,0.00008127926,0.002722699],"study_design_scores_gemma":[0.0003118953,0.004818295,0.01738727,0.0000256187,0.00008338918,0.0003250577,0.0000811211,0.0008878573,0.9741684,0.00004417583,0.001853659,0.00001323033],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970536,0.0009722941,0.0009369676,0.00009666372,0.00004603437,0.00002988315,0.0002830736,0.00007961418,0.000501766],"genre_scores_gemma":[0.9902469,0.001693116,0.002270275,0.00009908191,0.00005040706,0.0001276593,0.0007501379,0.00003649082,0.004725832],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001629856,"threshold_uncertainty_score":0.005452394,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01504316216709191,"score_gpt":0.2158449487217779,"score_spread":0.2008017865546859,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}