{"id":"W3155195921","doi":"10.1016/s2352-3026(21)00060-0","title":"Outcomes in patients treated with chimeric antigen receptor T-cell therapy who were admitted to intensive care (CARTTAS): an international, multicentre, observational cohort study","year":2021,"lang":"en","type":"article","venue":"The Lancet Haematology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":99,"is_retracted":false,"has_abstract":false,"ca_institutions":"Sinai Health System; Canada Research Chairs; University of Toronto","funders":"","keywords":"Medicine; Hazard ratio; Intensive care; Intensive care unit; Cytokine release syndrome; Cohort study; Cohort; Observational study; Proportional hazards model; Internal medicine; Retrospective cohort study; Emergency medicine; Chimeric antigen receptor; Pediatrics; Intensive care medicine; Confidence interval; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001863186,0.0002428446,0.001048704,0.0001525155,0.0000738412,0.00003127953,0.0003514657,0.0000870403,0.001272498],"category_scores_gemma":[0.0002200046,0.000157127,0.00006286555,0.0004544676,0.00008286144,0.00009193867,0.0001055415,0.0003363021,0.00006193927],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001447981,"about_ca_system_score_gemma":0.0001519413,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003150926,"about_ca_topic_score_gemma":0.0006336718,"domain_scores_codex":[0.9977834,0.0004176708,0.0003554387,0.0005111955,0.0005179028,0.0004144243],"domain_scores_gemma":[0.9973433,0.0001799019,0.0001073105,0.0007509675,0.001490241,0.0001283059],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002829657,0.0008739643,0.9875934,0.00001823527,0.0003686204,0.000204268,0.00545548,0.00001307012,0.001080679,0.00001114616,0.0006834619,0.0008680318],"study_design_scores_gemma":[0.009593734,0.001002931,0.9783409,0.00004346371,0.00003573842,0.00002966774,0.00597604,0.00005131848,0.002401098,0.000002620263,0.002358041,0.000164485],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993148,0.0001156903,0.000002608821,0.003484725,0.0001797311,0.002276593,0.0000531398,0.00005733448,0.0006821628],"genre_scores_gemma":[0.9939078,0.0001530605,0.0001907439,0.003624834,0.00009003343,0.0001781568,0.0006585193,0.00004612545,0.001150732],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009252523,"threshold_uncertainty_score":0.9996405,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05996188039825393,"score_gpt":0.3553764475528005,"score_spread":0.2954145671545465,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}