{"id":"W3155332101","doi":"10.1016/j.xpro.2021.100479","title":"Structural and biophysical characterization of the nucleosome-binding PZP domain","year":2021,"lang":"en","type":"article","venue":"STAR Protocols","topic":"Plant Molecular Biology Research","field":"Agricultural and Biological Sciences","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"National Institute of General Medical Sciences; National Institutes of Health; National Cancer Institute; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institute on Aging","keywords":"Nucleosome; Zinc finger; PHD finger; Histone acetyltransferase; Histone; Biophysics; Characterization (materials science); DNA; Chemistry; Protein subunit; Chromatosome; Computational biology; Biology; Cell biology; Biochemistry; Nanotechnology; Gene; Materials science; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002392508,0.0001827844,0.0001527565,0.000112289,0.0002308767,0.0001542024,0.0003641026,0.0002270284,0.0008495374],"category_scores_gemma":[0.0004300892,0.0001472971,0.0001458125,0.0002185805,0.000171077,0.0001829787,0.0001942311,0.0008193846,0.0002930452],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000452395,"about_ca_system_score_gemma":0.000206709,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003234478,"about_ca_topic_score_gemma":0.00276592,"domain_scores_codex":[0.9998976,0.00001052884,0.000006130917,0.00002030137,0.00004866367,0.00001679446],"domain_scores_gemma":[0.9998484,0.00003844918,0.00002200539,0.00002010481,0.00003148305,0.00003955968],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003941126,0.0000309772,0.0004715826,0.00002204365,0.000003067729,0.00002475406,0.00002428511,0.0004102261,0.9977124,0.0001830976,0.0001071465,0.0009711136],"study_design_scores_gemma":[0.00001841318,0.00008807832,0.01997473,0.00000664712,0.0000119418,0.0002143199,0.00005490034,0.01112382,0.9625099,0.0001855252,0.005796354,0.00001542639],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.9871678,0.0009241115,0.009066277,0.0002361252,0.00002620577,0.00001850974,0.00108573,0.00005430284,0.001420953],"genre_scores_gemma":[0.9865442,0.0006572263,0.007656226,0.00007239971,0.00001215622,0.0000221726,0.003356092,0.00003325088,0.001646318],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.003234478,"threshold_uncertainty_score":0.006431282,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0235811512137157,"score_gpt":0.2687490785461134,"score_spread":0.2451679273323977,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}