{"id":"W3155353611","doi":"10.1039/d0nj06182d","title":"Mononuclear copper(<scp>i</scp>) complexes of triphenylphosphine and <i>N</i>,<i>N</i>′-disubstituted thioureas as potential DNA binding chemotherapeutics","year":2021,"lang":"en","type":"article","venue":"New Journal of Chemistry","topic":"Metal complexes synthesis and properties","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Université de Montréal; Higher Education Commission, Pakistan","keywords":"Chemistry; Triphenylphosphine; Bromide; Copper; DNA; Stereochemistry; Medicinal chemistry; Organic chemistry; Biochemistry; Catalysis","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002441247,0.0002321464,0.0007810536,0.00003973706,0.00007130086,0.00005095779,0.0001715642,0.0001568915,0.0004737615],"category_scores_gemma":[0.0007238014,0.0001884654,0.0002743134,0.0001906851,0.0001450803,0.000110818,0.00007113232,0.0003846059,0.000004606359],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002978561,"about_ca_system_score_gemma":0.0004751744,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001060944,"about_ca_topic_score_gemma":4.056413e-7,"domain_scores_codex":[0.9982941,0.00003251173,0.0007103043,0.0002007982,0.0005224441,0.0002398529],"domain_scores_gemma":[0.9982469,0.0001438535,0.0005213407,0.0002263068,0.0003972805,0.0004643101],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002672518,0.0001332673,0.0004974577,0.0003817097,0.0003695101,0.0001155797,0.0003895795,0.00001269653,0.9921617,0.00001450979,0.004085627,0.00157114],"study_design_scores_gemma":[0.002330942,0.0001702403,0.000478596,0.0003848743,0.0004312609,0.002090964,0.0009063176,0.00005839429,0.9783574,0.0001503232,0.01455417,0.00008655206],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9831118,0.01075633,0.00007360087,0.001194344,0.00009421467,0.00006689724,0.0000108559,0.00001550884,0.004676467],"genre_scores_gemma":[0.9924883,0.00164352,0.002698663,0.0006903373,0.0004974192,3.89894e-7,0.000009405198,0.00004106012,0.001930885],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01380431,"threshold_uncertainty_score":0.7685396,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02288845238824578,"score_gpt":0.2504902228555776,"score_spread":0.2276017704673318,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}