{"id":"W3155424183","doi":"10.1016/j.scr.2021.102355","title":"Human induced pluripotent stem cell (hiPSC) line UOMi006-A derived from PBMCs of a patient with Kearns-Sayre syndrome","year":2021,"lang":"en","type":"article","venue":"Stem Cell Research","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Boniface Hospital; University of Manitoba","funders":"Canadian Institutes of Health Research","keywords":"Induced pluripotent stem cell; Heteroplasmy; Kearns–Sayre syndrome; Peripheral blood mononuclear cell; Biology; Mitochondrial DNA; Molecular biology; Cell culture; Genetics; Embryonic stem cell; Gene; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001195831,0.0002052432,0.0004269358,0.000439844,0.0004264161,0.0002602981,0.0001630472,0.0005316184,0.004064339],"category_scores_gemma":[0.0004275711,0.0001139647,0.0002070795,0.000407349,0.0002071597,0.0001628204,0.0002935866,0.0007238815,0.001058761],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001227105,"about_ca_system_score_gemma":0.0002293018,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006819291,"about_ca_topic_score_gemma":0.0007597745,"domain_scores_codex":[0.9998437,0.00001980206,0.00002663564,0.00004857416,0.00004195989,0.0000193648],"domain_scores_gemma":[0.9998854,0.00003618437,0.000006679096,0.00001986685,0.00001748091,0.00003435746],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000474484,0.0002882329,0.01231957,0.0002119121,0.00004782996,0.03616986,0.0006442429,0.0005362446,0.9112327,0.002061272,0.00488979,0.03112396],"study_design_scores_gemma":[0.000374872,0.002445166,0.06463917,0.0001306867,0.0001894922,0.2014716,0.0008511498,0.005830883,0.6297039,0.001986092,0.0922722,0.0001047396],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9572296,0.003140522,0.01646955,0.001389944,0.0006835536,0.0006895201,0.005451534,0.0005115495,0.01443415],"genre_scores_gemma":[0.9687433,0.001386804,0.01387143,0.0007367989,0.0001103476,0.0002703101,0.006641022,0.00006117774,0.008178808],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004064339,"threshold_uncertainty_score":0.01359659,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04797088196007362,"score_gpt":0.2944326004182603,"score_spread":0.2464617184581867,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}