{"id":"W3155424183","doi":"10.1016/j.scr.2021.102355","title":"Human induced pluripotent stem cell (hiPSC) line UOMi006-A derived from PBMCs of a patient with Kearns-Sayre syndrome","year":2021,"lang":"en","type":"article","venue":"Stem Cell Research","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Boniface Hospital; University of Manitoba","funders":"Canadian Institutes of Health Research","keywords":"Induced pluripotent stem cell; Heteroplasmy; Kearns–Sayre syndrome; Peripheral blood mononuclear cell; Biology; Mitochondrial DNA; Molecular biology; Cell culture; Genetics; Embryonic stem cell; Gene; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002984589,0.0002135038,0.0003262171,0.0001126693,0.0001732744,0.00003737374,0.0002718316,0.0003190578,0.0002872778],"category_scores_gemma":[0.00001385953,0.0001867597,0.0001173779,0.0002934142,0.0001237461,0.000004521379,0.0003602272,0.0004396462,0.00006957402],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003824718,"about_ca_system_score_gemma":0.0003652437,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001573706,"about_ca_topic_score_gemma":0.0002085697,"domain_scores_codex":[0.997137,0.0007151783,0.0003919864,0.0007085392,0.0005523438,0.0004950226],"domain_scores_gemma":[0.9982111,0.00005920559,0.0001317365,0.0008050476,0.0005767914,0.000216109],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002612747,0.0002720502,0.0005821309,0.00009134655,0.00004950896,0.0002857566,0.0003220918,0.00004794195,0.9964527,0.00001386192,0.0004843414,0.001136936],"study_design_scores_gemma":[0.001310727,0.002394075,0.0005515037,0.00004811571,0.00001885501,0.00004873323,0.002269693,0.00001368783,0.9864701,0.00001668297,0.00664532,0.000212478],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945038,0.0009877892,0.0001674751,0.00007832645,0.0002266925,0.0004122822,0.00006732655,0.00001295154,0.003543375],"genre_scores_gemma":[0.991261,0.00009413774,0.0003400028,0.00006593471,0.000135081,0.00005115111,0.0002631418,0.00004430275,0.007745256],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00998263,"threshold_uncertainty_score":0.761584,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04797088196007362,"score_gpt":0.2944326004182603,"score_spread":0.2464617184581867,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}