{"id":"W3155544647","doi":"10.1371/journal.pbio.3001162","title":"The methodological quality of 176,620 randomized controlled trials published between 1966 and 2018 reveals a positive trend but also an urgent need for improvement","year":2021,"lang":"en","type":"article","venue":"PLoS Biology","topic":"Meta-analysis and systematic reviews","field":"Decision Sciences","cited_by":107,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"ZonMw","keywords":"Biology; Quality (philosophy); Randomized controlled trial; Internal medicine; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch","metaepi_broad"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.2692786,0.002183827,0.007908754,0.03674286,0.001747405,0.007345416,0.003350845,0.003083671,0.006315897],"category_scores_gemma":[0.5955018,0.002200649,0.01181223,0.03947655,0.003829635,0.005882101,0.005111435,0.002984342,0.002499176],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00716365,"about_ca_system_score_gemma":0.01720173,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005784696,"about_ca_topic_score_gemma":0.0104914,"domain_scores_codex":[0.6040654,0.1196847,0.2180554,0.016568,0.04004871,0.001577791],"domain_scores_gemma":[0.3345241,0.4378484,0.1270268,0.04494692,0.05378321,0.001870465],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.00370778,0.0001321368,0.08296534,0.5098364,0.0448529,0.0008120999,0.00428817,0.001486693,0.002578674,0.007609576,0.02390686,0.3178234],"study_design_scores_gemma":[0.002269369,0.0009262068,0.1873429,0.4015722,0.1153196,0.002258744,0.002283509,0.001243519,0.00499791,0.02384862,0.257378,0.0005595184],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.03235315,0.8805104,0.02960797,0.0102296,0.002257644,0.004327822,0.03488525,0.0003465632,0.005481544],"genre_scores_gemma":[0.3984943,0.4133403,0.1020278,0.01562567,0.002566639,0.01960843,0.04436773,0.0009830889,0.002986056],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.9920912,"threshold_uncertainty_score":0.9011096,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.857873822209687,"score_gpt":0.5975775121062752,"score_spread":0.2602963101034118,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}