{"id":"W3155565607","doi":"10.1016/j.lungcan.2021.04.006","title":"Durability of CNS disease control in NSCLC patients with brain metastases treated with immune checkpoint inhibitors plus cranial radiotherapy","year":2021,"lang":"en","type":"article","venue":"Lung Cancer","topic":"Brain Metastases and Treatment","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"","keywords":"Medicine; Radiation therapy; Oncology; Immune checkpoint; Internal medicine; Disease; Prophylactic cranial irradiation; Immune system; Immunotherapy; Cancer; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004674292,0.0001276184,0.0006099197,0.0001917583,0.0002169199,0.0004019473,0.0002344868,0.00023201,0.001179143],"category_scores_gemma":[0.001386134,0.00006495621,0.0005583448,0.0002581189,0.0001633525,0.0003617521,0.000200733,0.0005751857,0.0001595408],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005037863,"about_ca_system_score_gemma":0.0004361751,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001544039,"about_ca_topic_score_gemma":0.003151294,"domain_scores_codex":[0.9997945,0.00003665739,0.00002217848,0.00004073803,0.00003641013,0.00006958601],"domain_scores_gemma":[0.9993119,0.0001640897,0.0002453073,0.00005726799,0.00006862479,0.0001528756],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.05934951,0.001164526,0.6473418,0.0004004886,0.001953663,0.0009800073,0.0003429585,0.002804273,0.01814011,0.0002442958,0.001505025,0.2657733],"study_design_scores_gemma":[0.0005582094,0.01605264,0.9738411,0.00004915233,0.00118441,0.001194367,0.0001397806,0.0008793763,0.002961921,0.0002143571,0.002904129,0.00002045416],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930895,0.004785036,0.0001201459,0.0001406726,0.00003899827,0.00001328036,0.0002883545,0.000007860341,0.001516171],"genre_scores_gemma":[0.9986905,0.0004806735,0.00002939318,0.00005575171,0.00002427985,0.000006021208,0.0003277588,0.000002065368,0.0003834366],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001544039,"threshold_uncertainty_score":0.003944576,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005355088471290016,"score_gpt":0.2574501946854422,"score_spread":0.2520951062141522,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}