{"id":"W3155565607","doi":"10.1016/j.lungcan.2021.04.006","title":"Durability of CNS disease control in NSCLC patients with brain metastases treated with immune checkpoint inhibitors plus cranial radiotherapy","year":2021,"lang":"en","type":"article","venue":"Lung Cancer","topic":"Brain Metastases and Treatment","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"","keywords":"Medicine; Radiation therapy; Oncology; Immune checkpoint; Internal medicine; Disease; Prophylactic cranial irradiation; Immune system; Immunotherapy; Cancer; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001502889,0.0002521509,0.0006728882,0.000074323,0.00003893455,0.00001230968,0.00004634568,0.00004141854,0.0005484134],"category_scores_gemma":[0.00005513328,0.0001605395,0.0001448991,0.0003702423,0.0001298611,0.00007468734,0.0000121295,0.0001272364,5.543288e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004852506,"about_ca_system_score_gemma":0.0005896367,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001500281,"about_ca_topic_score_gemma":0.0005861254,"domain_scores_codex":[0.9983935,0.0001689227,0.0003990303,0.000395837,0.0003647373,0.0002780211],"domain_scores_gemma":[0.9989281,0.0001037473,0.0001578631,0.0004191412,0.000199631,0.0001914931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01419731,0.001720426,0.9758157,0.000312498,0.001256806,0.0003973191,0.0003352608,0.000540881,0.001699099,0.00002043354,0.0001738243,0.003530493],"study_design_scores_gemma":[0.04544067,0.0008937831,0.9463981,0.0006573975,0.0008354145,0.000006761028,0.00008185609,0.0005016401,0.004593362,0.000004826233,0.0003556074,0.0002305978],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908152,0.004927715,0.0002507519,0.002189164,0.00006347016,0.001143612,0.000541074,0.00002633552,0.00004265414],"genre_scores_gemma":[0.9984886,0.00007209591,0.0004046246,0.0004248519,0.00006001546,0.0001883528,0.0002039037,0.00003782032,0.0001197377],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03124336,"threshold_uncertainty_score":0.6546609,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005355088471290016,"score_gpt":0.2574501946854422,"score_spread":0.2520951062141522,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}