{"id":"W3155588809","doi":"10.1002/smll.202008198","title":"Optimized Photoactivatable Lipid Nanoparticles Enable Red Light Triggered Drug Release","year":2021,"lang":"en","type":"article","venue":"Small","topic":"Photochromic and Fluorescence Chemistry","field":"Materials Science","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"NanoMedicines Innovation Network; BC Innovation Council; University of British Columbia","funders":"National Science Foundation","keywords":"Chemistry; Drug; Liposome; In vivo; Biophysics; Drug delivery; Extravasation; Doxorubicin; Azobenzene; Nile red; Nanoparticle; Cytotoxicity; In vitro; Pharmacology; Nanotechnology; Biochemistry; Molecule; Materials science; Biology; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009238034,0.0002373278,0.0001097191,0.00008735742,0.00005691926,0.0002034817,0.0001214641,0.0002274557,0.0007630726],"category_scores_gemma":[0.00009072338,0.000104964,0.0001208796,0.00007864033,0.0001481178,0.000198503,0.0001367485,0.0003018973,0.000277272],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002647394,"about_ca_system_score_gemma":0.0001344019,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003043207,"about_ca_topic_score_gemma":0.0005988957,"domain_scores_codex":[0.9999552,0.00000545264,0.00000404796,0.0000139653,0.00001197842,0.00000946412],"domain_scores_gemma":[0.9999527,0.00000953866,0.00002044167,0.000004465856,0.000007841187,0.000005102114],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001596598,0.000004519623,0.00002157911,0.00001521978,0.000001008799,0.00001185793,0.000005790181,0.00009935541,0.9989661,0.00009559128,0.00001288847,0.0007501557],"study_design_scores_gemma":[0.000002957479,0.00003045977,0.0001520691,0.00000101528,0.000002208323,0.00002218956,0.000002815968,0.0004793951,0.998548,0.00001591482,0.000741391,0.000001521658],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9740334,0.0009267582,0.02199059,0.00008757145,0.00002231932,0.00005343974,0.0001805031,0.0002188056,0.002486691],"genre_scores_gemma":[0.9860005,0.0004827215,0.01016203,0.00003056453,0.000003374219,0.00003410289,0.0001505313,0.0000417496,0.003094501],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007630726,"threshold_uncertainty_score":0.002552688,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01382933636187501,"score_gpt":0.2122891135878867,"score_spread":0.1984597772260117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}