{"id":"W3155589128","doi":"10.1182/blood.v130.suppl_1.3403.3403","title":"Incremental Financial and Health-Related Burden of Novel Drugs Used in the Treatment of Relapsed and/or Refractory Multiple Myeloma (RRMM): A Meta-Analysis of Phase III Randomized Controlled Trials (RCTs)","year":2017,"lang":"en","type":"article","venue":"Blood","topic":"Pharmaceutical Economics and Policy","field":"Economics, Econometrics and Finance","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"","keywords":"Pomalidomide; Medicine; Randomized controlled trial; Internal medicine; Meta-analysis; Refractory (planetary science); Oncology; Multiple myeloma; Lenalidomide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03519944,0.003733433,0.01401774,0.002738399,0.0004725462,0.0040771,0.002183502,0.003172545,0.002734836],"category_scores_gemma":[0.05963265,0.002270928,0.05962416,0.003395299,0.00128793,0.002497773,0.002184671,0.004474234,0.0002597004],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002054888,"about_ca_system_score_gemma":0.001449314,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00318349,"about_ca_topic_score_gemma":0.00347814,"domain_scores_codex":[0.9681724,0.02346372,0.003752691,0.002342458,0.001623767,0.0006448763],"domain_scores_gemma":[0.9413648,0.04765363,0.006278383,0.0030326,0.001155138,0.0005154348],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.01937942,0.00003199631,0.004868126,0.00937469,0.9611973,0.00004289279,0.00002061411,0.001032397,0.0001216435,0.000128389,0.0001352722,0.003667194],"study_design_scores_gemma":[0.003651398,0.0005202293,0.003487268,0.0007029292,0.9901993,0.00004769476,0.00001822274,0.0005318001,0.0001151817,0.000389807,0.0003181564,0.00001798665],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.1255343,0.864453,0.005238656,0.0010257,0.000877924,0.0004133936,0.001374546,0.0001373413,0.00094518],"genre_scores_gemma":[0.9047846,0.08750474,0.004338232,0.001012342,0.0005764989,0.0004182372,0.0009385635,0.00006706112,0.0003596714],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.03519944,"threshold_uncertainty_score":0.1861547,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1858870700279212,"score_gpt":0.3730247050860721,"score_spread":0.1871376350581508,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}