{"id":"W3155777109","doi":"10.1186/s40168-021-01052-7","title":"Iron status influences non-alcoholic fatty liver disease in obesity through the gut microbiome","year":2021,"lang":"en","type":"article","venue":"Microbiome","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":150,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University and Génome Québec Innovation Centre","funders":"NIHR Imperial Biomedical Research Centre; Instituto de Salud Carlos III; Medical Research Council; Horizon 2020 Framework Programme; Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana; Conseil Régional Hauts-de-France; National Institute for Health and Care Research; Ministerio de Ciencia e Innovación; Generalitat Valenciana; Institut National de la Santé et de la Recherche Médicale; European Commission; École Polytechnique Fédérale de Lausanne; Università degli Studi di Roma Tor Vergata; CHIST-ERA; Trent University; Agence Nationale de la Recherche; Imperial College London; European Social Fund; Nottingham Trent University","keywords":"Biology; Fatty liver; Ferritin; Veillonella; Gut flora; Prevotella; Microbiome; Steatohepatitis; Physiology; Microbiology; Internal medicine; Biochemistry; Disease; Bioinformatics; Medicine; Genetics; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001654743,0.000299445,0.0002578518,0.00006729218,0.0002238578,0.00008294554,0.0003774849,0.0002059159,0.0001154094],"category_scores_gemma":[0.00003392484,0.0002459932,0.0001630461,0.0004203789,0.0002653103,0.00001530567,0.0003755378,0.0002225362,0.0001658097],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008489136,"about_ca_system_score_gemma":0.0004579526,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008685373,"about_ca_topic_score_gemma":0.0009174275,"domain_scores_codex":[0.9979494,0.0001593422,0.0003676937,0.0006818038,0.00008891643,0.0007529002],"domain_scores_gemma":[0.9988704,0.00001746268,0.0001107916,0.0007327669,0.0001075056,0.0001610761],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00005298117,0.0002218524,0.02458529,0.0001121641,0.00002584129,0.00005782787,0.0004429503,0.00002605843,0.9702951,0.00002013755,0.00395173,0.0002081109],"study_design_scores_gemma":[0.001016371,0.00008817706,0.4960222,0.00008636671,0.0000428113,0.00006494213,0.0001718686,0.000007602011,0.3226217,0.00004908322,0.1792972,0.0005316641],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99198,0.006069618,0.00008322197,0.0007235735,0.000256891,0.0003470647,0.0003029098,0.00001648566,0.0002202006],"genre_scores_gemma":[0.9931248,0.001608663,0.0006321534,0.00258659,0.0001648402,0.00002087437,0.0007033586,0.00003375356,0.001124966],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6476734,"threshold_uncertainty_score":0.9999992,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01137036799420108,"score_gpt":0.2652290175917341,"score_spread":0.253858649597533,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}