{"id":"W3155898306","doi":"10.1101/2021.04.13.21255409","title":"Efficacy of a nasal spray containing Iota-Carrageenan in the prophylaxis of COVID-19 in hospital personnel dedicated to patients care with COVID-19 disease A pragmatic multicenter, randomized, double-blind, placebo-controlled trial (CARR-COV-02)","year":2021,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Infection Control and Ventilation","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital du Sacré-Cœur de Montréal","funders":"","keywords":"Placebo; Medicine; Odds ratio; Nasal spray; Confidence interval; Incidence (geometry); Adverse effect; Randomized controlled trial; Clinical trial; Internal medicine; Clinical endpoint; Placebo-controlled study; Double blind; Nasal administration; Immunology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002425504,0.001182091,0.002868495,0.000461245,0.0004926416,0.001041737,0.0008410027,0.002036314,0.00379394],"category_scores_gemma":[0.003227579,0.0005377659,0.002190208,0.000409876,0.001041663,0.0006823471,0.000421538,0.00147965,0.0003279602],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007319469,"about_ca_system_score_gemma":0.001580403,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008477705,"about_ca_topic_score_gemma":0.001635493,"domain_scores_codex":[0.9983021,0.001105441,0.0001300423,0.0002227675,0.0001242085,0.0001153533],"domain_scores_gemma":[0.9982634,0.0005232354,0.0005823751,0.00007379048,0.0001414684,0.000415709],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9635369,0.009034156,0.000918842,0.002477151,0.001256177,0.00004291936,0.00006612055,0.0001267208,0.005174058,0.0000915874,0.0004234563,0.01685195],"study_design_scores_gemma":[0.8203356,0.175829,0.002179329,0.0001085527,0.0006103729,0.00002684258,0.00003996448,0.0001812459,0.0003113178,0.00004969999,0.0003147076,0.00001339],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9830263,0.01024231,0.0003924627,0.0006711739,0.0006658276,0.003646154,0.0003053638,0.00003743228,0.001013001],"genre_scores_gemma":[0.9896348,0.003429792,0.001536229,0.0007872381,0.000662955,0.003071793,0.0002644129,0.0000082467,0.0006044536],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00379394,"threshold_uncertainty_score":0.01282746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02233847919990178,"score_gpt":0.3134119396548272,"score_spread":0.2910734604549254,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}