{"id":"W3156019289","doi":"10.1016/j.ekir.2021.03.398","title":"POS-380 A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY OF ATRASENTAN IN PATIENTS WITH IGA NEPHROPATHY (THE ALIGN STUDY)","year":2021,"lang":"en","type":"article","venue":"Kidney International Reports","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Medicine; Proteinuria; Kidney disease; Nephropathy; Placebo; Renal function; Glomerulonephritis; Randomized controlled trial; Internal medicine; End-stage kidney disease; Disease; Kidney; Urology; Gastroenterology; Pathology; Endocrinology; Diabetes mellitus; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00105388,0.001568889,0.002477227,0.0004330825,0.0004779083,0.0008749711,0.0007639203,0.001707021,0.01268656],"category_scores_gemma":[0.0009746593,0.0006289239,0.00156068,0.0003244962,0.0009481464,0.001112623,0.0003422894,0.003055898,0.001813416],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004923393,"about_ca_system_score_gemma":0.0009997516,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007896955,"about_ca_topic_score_gemma":0.002109861,"domain_scores_codex":[0.9996909,0.0001508632,0.00002166664,0.0000581291,0.00002540621,0.00005305511],"domain_scores_gemma":[0.9995809,0.0001010291,0.00008222044,0.00003669552,0.00003508343,0.0001641458],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9634179,0.00957965,0.0005947613,0.0009265094,0.0009471797,0.00004500264,0.00003736426,0.0002262509,0.003894875,0.0002231591,0.001893798,0.01821355],"study_design_scores_gemma":[0.94733,0.04993699,0.001050763,0.00003477528,0.0002584964,0.00002225236,0.00001640732,0.0002169051,0.0002558603,0.0001198776,0.0007467997,0.00001084593],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9684855,0.01220305,0.001143131,0.001218562,0.001176153,0.004889945,0.002876488,0.0004709726,0.007536252],"genre_scores_gemma":[0.9724646,0.006544926,0.002692664,0.003360565,0.0008638285,0.004576731,0.002826327,0.00006043457,0.006609877],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01268656,"threshold_uncertainty_score":0.04244071,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01287873290170733,"score_gpt":0.3029754807241705,"score_spread":0.2900967478224632,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}