{"id":"W3156019974","doi":"10.1101/2021.04.14.439908","title":"Integrative Clinical and Molecular Characterization of Translocation Renal Cell Carcinoma","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; William Osler Health System","funders":"","keywords":"Renal cell carcinoma; Chromosomal translocation; Immunophenotyping; Biology; Kidney cancer; CD8; Cancer research; Somatic cell; Breakpoint; Immune system; Gene; Flow cytometry; Immunology; Pathology; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008281068,0.0001638136,0.0003782672,0.0008768256,0.0002389936,0.0005796534,0.0002194737,0.0002105303,0.001496126],"category_scores_gemma":[0.0007496375,0.00008754056,0.0002272157,0.0008449301,0.0002169104,0.0001781867,0.0004633231,0.0002384896,0.0002907113],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003111915,"about_ca_system_score_gemma":0.000448833,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009099962,"about_ca_topic_score_gemma":0.001358623,"domain_scores_codex":[0.9996703,0.00007741711,0.00003238926,0.00009742486,0.00007048975,0.00005191673],"domain_scores_gemma":[0.9995919,0.00007360847,0.000111043,0.00007621017,0.00007763897,0.00006958153],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001663276,0.0002050511,0.7535765,0.0001584773,0.000243706,0.001519432,0.0003538909,0.001017093,0.1922719,0.0007304836,0.001089946,0.04717017],"study_design_scores_gemma":[0.0000956514,0.0008222639,0.9645957,0.0000155825,0.0002018218,0.00616208,0.0003253505,0.001860597,0.01705404,0.0005383877,0.008312452,0.00001611045],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957041,0.0006409425,0.000986375,0.00007396699,0.000006477485,0.00004686537,0.001150805,0.0000242034,0.001366182],"genre_scores_gemma":[0.9966112,0.0001477478,0.001238061,0.00003941641,0.000009063413,0.0000200405,0.001672384,0.00001077955,0.0002513231],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001496126,"threshold_uncertainty_score":0.005005062,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01868378528087879,"score_gpt":0.2477265038363787,"score_spread":0.2290427185554999,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}