{"id":"W3156149043","doi":"10.1139/cjpp-2020-0547","title":"Protective effects of selenium in tacrolimus-induced lung toxicity: potential role of heme oxygenase 1","year":2021,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Heme oxygenase; Malondialdehyde; Myeloperoxidase; Toxicity; Glutathione peroxidase; Oxidative stress; Superoxide dismutase; Glutathione; Bronchoalveolar lavage; Pharmacology; Chemistry; Lung; Nitric oxide synthase; Nitric oxide; Internal medicine; Medicine; Heme; Inflammation; Biochemistry; Enzyme","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001146544,0.000271204,0.0003345611,0.0002347859,0.0001324579,0.0001579995,0.0001436527,0.0003156409,0.0007924636],"category_scores_gemma":[0.00009529215,0.00007314218,0.0001729157,0.0001023259,0.0001904317,0.0002171548,0.0001399783,0.000359345,0.00007163312],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001071552,"about_ca_system_score_gemma":0.0001739696,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003343407,"about_ca_topic_score_gemma":0.000935989,"domain_scores_codex":[0.9999431,0.00001582019,0.000005090896,0.000008895572,0.00001125994,0.0000158521],"domain_scores_gemma":[0.9999151,0.00001112552,0.00002486833,0.000007072477,0.00001741817,0.00002440308],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001586868,0.0002214824,0.001263068,0.0001772525,0.00002304969,0.0001919084,0.00003308212,0.00004853227,0.987617,0.00007485613,0.00004430847,0.008718564],"study_design_scores_gemma":[0.00007049102,0.009247393,0.02552209,0.00003350078,0.0001168512,0.0006250005,0.0001642281,0.000527943,0.9614055,0.0001455666,0.002130928,0.00001051869],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931148,0.005290053,0.000821157,0.0001337815,0.00003149228,0.00001563986,0.00004600906,0.00002416947,0.0005229078],"genre_scores_gemma":[0.9957126,0.002316734,0.0006543916,0.00005657988,0.00001488226,0.00001395097,0.00005713219,0.000002730882,0.001171035],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007924636,"threshold_uncertainty_score":0.002651095,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003742532164743156,"score_gpt":0.2300231093794411,"score_spread":0.226280577214698,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}