{"id":"W3156312718","doi":"10.3390/toxins13040264","title":"Developing a Consistent, Reproducible Botulinum Toxin Type A Dosing Method for Upper Limb Tremor by Kinematic Analysis","year":2021,"lang":"en","type":"article","venue":"Toxins","topic":"Neurological disorders and treatments","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre; Lawson Health Research Institute; Western University","funders":"Parkinsonfonden; Ontario Centres of Excellence; London Health Sciences Centre; Mitacs; National Parkinson Foundation","keywords":"Elbow; Dosing; Kinematics; Physical medicine and rehabilitation; Medicine; Essential tremor; Botulinum toxin; Dose; Wrist; Adverse effect; Physical therapy; Anesthesia; Surgery; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002085741,0.0006149064,0.0005111402,0.0008000169,0.0002330367,0.0005175035,0.0005576382,0.0003783577,0.0004490087],"category_scores_gemma":[0.00448151,0.0003186256,0.0003818217,0.0004372892,0.0003556793,0.0003947216,0.0005557919,0.0003339511,0.0003039385],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000402235,"about_ca_system_score_gemma":0.0006310678,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009232466,"about_ca_topic_score_gemma":0.001882206,"domain_scores_codex":[0.9976421,0.0005756913,0.0003329167,0.0004013787,0.000973786,0.00007409661],"domain_scores_gemma":[0.998171,0.0003721913,0.0006049586,0.0002573512,0.0005553372,0.00003919371],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004613556,0.0002685346,0.01247498,0.0002791212,0.00008551546,0.0001087456,0.0001874423,0.004642417,0.7422377,0.0003438621,0.0003541142,0.2385563],"study_design_scores_gemma":[0.0002321663,0.007750747,0.09855486,0.0001104273,0.0002668701,0.002629747,0.0001894059,0.04522436,0.8360509,0.0006146647,0.008188459,0.0001873647],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.3566778,0.001218962,0.6380455,0.0001163254,0.00007775546,0.001378025,0.0002860462,0.0008011695,0.0013984],"genre_scores_gemma":[0.5636227,0.0008390415,0.4331163,0.0001185303,0.00003287431,0.0008996289,0.0003111924,0.0001249192,0.0009347321],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002085741,"threshold_uncertainty_score":0.01103061,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06243336832745632,"score_gpt":0.3606942353216566,"score_spread":0.2982608669942002,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}