{"id":"W3156722905","doi":"10.1097/01.hjh.0000748456.01450.d7","title":"BONE MORPHOGENETIC PROTEIN 2 PROMOTES HUMAN TROPHOBLAST CELL INVASION AND ENDOTHELIAL-LIKE TUBE FORMATION THROUGH ID1-MEDIATED UP-REGULATION OF IGF BINDING PROTEIN-3","year":2021,"lang":"en","type":"article","venue":"Journal of Hypertension","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"","keywords":"Angiogenesis; Trophoblast; Cell biology; Matrigel; Biology; Bone morphogenetic protein; IGFBP3; Growth factor; Endothelial stem cell; Bone morphogenetic protein 2; Placentation; Vascular endothelial growth factor; Cancer research; Placenta; Receptor; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008856536,0.0003343101,0.0001490256,0.0002569386,0.0001128546,0.000175563,0.00009603837,0.0001119209,0.001621628],"category_scores_gemma":[0.0000635128,0.00009820227,0.0002662054,0.0001216857,0.0001644107,0.00007284475,0.0001627597,0.0003738157,0.000363697],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002161272,"about_ca_system_score_gemma":0.0002351988,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001180911,"about_ca_topic_score_gemma":0.001661815,"domain_scores_codex":[0.999934,0.00001000831,0.000004702957,0.000009444849,0.00002354057,0.00001841472],"domain_scores_gemma":[0.9999675,0.000006157374,0.000008077877,0.000002586996,0.00000464274,0.00001108584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001969712,0.00004588205,0.0003899799,0.00008114531,0.00000625346,0.00009149806,0.00002206965,0.00005222135,0.9973339,0.00009507698,0.0001768378,0.001508177],"study_design_scores_gemma":[0.00008158464,0.0003957938,0.02232551,0.00001523076,0.00003633738,0.0004334854,0.00006442918,0.001863419,0.9676027,0.00008210205,0.007092907,0.00000652023],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9836384,0.004774912,0.003899418,0.0002884954,0.0001022908,0.00007968837,0.001269337,0.0002468211,0.005700614],"genre_scores_gemma":[0.9867306,0.002107789,0.003850055,0.0001451716,0.00002403359,0.0000909748,0.001286591,0.00002302703,0.005741782],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001621628,"threshold_uncertainty_score":0.005424917,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03511479356300968,"score_gpt":0.2377990737892594,"score_spread":0.2026842802262497,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}