{"id":"W3156941576","doi":"10.3390/v13040678","title":"The Intersection of Age and Influenza Severity: Utility of Ferrets for Dissecting the Age-Dependent Immune Responses and Relevance to Age-Specific Vaccine Development","year":2021,"lang":"en","type":"review","venue":"Viruses","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Nova Scotia Health Authority; Izaak Walton Killam Health Centre; Dalhousie University","funders":"Canadian Institutes of Health Research; Genome Canada","keywords":"Vaccination; Virus; Immunology; Disease; Immune system; Virology; Biology; Viral shedding; Influenza A virus; Host factors; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002119852,0.0003875815,0.001628738,0.0001569155,0.0004615149,0.00007293607,0.0002391609,0.0001432008,0.000009461927],"category_scores_gemma":[0.007396524,0.0002175931,0.0002032502,0.00037774,0.0002696668,0.00007056753,0.0006576177,0.0004724838,0.000001635307],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001589276,"about_ca_system_score_gemma":0.0002729536,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001020351,"about_ca_topic_score_gemma":0.0003562268,"domain_scores_codex":[0.9970746,0.0004451334,0.001151529,0.0004964419,0.0004653881,0.0003668911],"domain_scores_gemma":[0.9946237,0.003830308,0.0004325421,0.0006547591,0.0003795763,0.00007911656],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001423707,0.00007335654,0.0002548819,0.01102564,0.0008044257,0.00008634015,0.002106697,1.958629e-7,0.0006366891,0.00005197035,0.0004782203,0.9830579],"study_design_scores_gemma":[0.0005121281,0.0001973235,0.008854787,0.0105824,0.0002688574,0.00004483772,0.000793526,8.986454e-7,0.001450663,0.00002475985,0.9770745,0.0001953378],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03860948,0.9586208,0.00004831747,0.00004530273,0.0002174492,0.002295526,0.00006701556,0.00002465076,0.00007145689],"genre_scores_gemma":[0.005758318,0.9928033,0.0005391155,0.0001203199,0.00009469141,0.000388714,0.00000986421,0.00005033896,0.0002353171],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9828625,"threshold_uncertainty_score":0.8873191,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2439702959664201,"score_gpt":0.4503424569568433,"score_spread":0.2063721609904232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}