{"id":"W3156941576","doi":"10.3390/v13040678","title":"The Intersection of Age and Influenza Severity: Utility of Ferrets for Dissecting the Age-Dependent Immune Responses and Relevance to Age-Specific Vaccine Development","year":2021,"lang":"en","type":"review","venue":"Viruses","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Nova Scotia Health Authority; Izaak Walton Killam Health Centre; Dalhousie University","funders":"Canadian Institutes of Health Research; Genome Canada","keywords":"Vaccination; Virus; Immunology; Disease; Immune system; Virology; Biology; Viral shedding; Influenza A virus; Host factors; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006747812,0.0006343243,0.001460825,0.001672772,0.0001383145,0.0007565356,0.0005424391,0.0008899549,0.001685463],"category_scores_gemma":[0.0009078078,0.0001884963,0.0007423565,0.0009136125,0.0003837561,0.001078085,0.0004139389,0.001148077,0.0005754418],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004398148,"about_ca_system_score_gemma":0.0006527785,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001144815,"about_ca_topic_score_gemma":0.001502313,"domain_scores_codex":[0.9998019,0.00005436729,0.00003384271,0.0000417779,0.0000549767,0.00001316412],"domain_scores_gemma":[0.9994423,0.0003717435,0.00007400468,0.00001473095,0.00007892978,0.00001842568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001901403,0.00006717541,0.0006039679,0.04013481,0.0002261797,0.0001234229,0.0000836498,0.000222828,0.00538712,0.003029268,0.009219578,0.9407119],"study_design_scores_gemma":[0.00003587588,0.0006069401,0.007027822,0.02015209,0.0009880604,0.002312351,0.0001686401,0.0002163052,0.003629506,0.00353901,0.961264,0.0000593369],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001933375,0.9990497,0.0001108182,0.0001250774,0.00008940318,0.000004826604,0.00002150326,0.000004258809,0.0004010276],"genre_scores_gemma":[0.001393746,0.9978593,0.0002567532,0.0001329049,0.00007531374,0.00001156636,0.00003086492,0.000001487752,0.0002380867],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001685463,"threshold_uncertainty_score":0.00563848,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2439702959664201,"score_gpt":0.4503424569568433,"score_spread":0.2063721609904232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}