{"id":"W3157151159","doi":"10.15173/sciential.v1i4.2435","title":"Review on Anti-CD19 CAR T Therapy against B-Cell Malignancies and Future Implications","year":2020,"lang":"en","type":"article","venue":"Sciential - McMaster Undergraduate Science Journal","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Chimeric antigen receptor; Medicine; CD19; Immunotherapy; Clinical trial; Cell therapy; Targeted therapy; Oncology; Immune system; Immunology; Cancer; Internal medicine; Cell; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015128,0.0002678457,0.0004128648,0.0003243005,0.001043485,0.000572327,0.0006564483,0.00005938543,0.0007707772],"category_scores_gemma":[0.00007968154,0.0001906264,0.0001924274,0.002206281,0.001102478,0.000551586,0.0001651576,0.0006722403,0.00008761862],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001318743,"about_ca_system_score_gemma":0.0008042993,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002509921,"about_ca_topic_score_gemma":9.201302e-7,"domain_scores_codex":[0.9964822,0.0000991133,0.0004586862,0.0007234503,0.001466296,0.0007702563],"domain_scores_gemma":[0.9977887,0.00003044785,0.0002115265,0.0004063903,0.000519458,0.001043437],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008711061,0.0001275606,0.0007205833,0.0001592302,0.00002157099,0.00002769342,0.0004104923,0.000008343541,0.936829,0.0001675585,0.01222155,0.0492193],"study_design_scores_gemma":[0.007246503,0.003111224,0.01495616,0.001905531,0.0001431596,0.001764774,0.0009023166,0.0008738068,0.09651623,0.0008909519,0.8706921,0.0009972892],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6144425,0.01482522,0.0003352434,0.3523048,0.001213044,0.001425418,0.00002126959,0.00009607682,0.01533642],"genre_scores_gemma":[0.7781615,0.1576706,0.001321887,0.05635125,0.002538077,0.00001949047,0.00001002797,0.00006811722,0.0038591],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8584705,"threshold_uncertainty_score":0.843947,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04829899014593807,"score_gpt":0.3227835862838425,"score_spread":0.2744845961379044,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}