{"id":"W3157192435","doi":"10.3390/cells10050994","title":"Mechanosensitive Regulation of Fibrosis","year":2021,"lang":"en","type":"review","venue":"Cells","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Connaught Fund; University of Toronto","keywords":"Proinflammatory cytokine; Fibrosis; Inflammation; Context (archaeology); Mechanosensitive channels; Mechanobiology; Immune system; Cell biology; Mechanotransduction; Tissue remodeling; Neuroscience; Biology; Immunology; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000198045,0.0005629339,0.0006207644,0.001112192,0.000203688,0.0006612299,0.0003678246,0.000582381,0.003818339],"category_scores_gemma":[0.0002092401,0.0001591409,0.0002490741,0.0009229076,0.000288915,0.0006616886,0.0005599969,0.000882157,0.00210354],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003575735,"about_ca_system_score_gemma":0.000509568,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003707445,"about_ca_topic_score_gemma":0.000762526,"domain_scores_codex":[0.9999295,0.00001049629,0.000007855,0.00001376764,0.00002817422,0.00001018559],"domain_scores_gemma":[0.9999402,0.00002206857,0.00001038817,0.000002445335,0.000015727,0.000009175085],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005322646,0.00004703248,0.0001213182,0.0129428,0.00005630377,0.0002181032,0.00006972069,0.0004223173,0.01141981,0.01035235,0.02784646,0.9364505],"study_design_scores_gemma":[0.000008379776,0.00006189467,0.0007609182,0.001453636,0.0000329201,0.0009689871,0.00003396672,0.00008909551,0.00175552,0.002960256,0.9918616,0.00001299512],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002382205,0.9965404,0.0002546549,0.0002162267,0.0002166459,0.000005348906,0.00003127021,0.00001469524,0.002482518],"genre_scores_gemma":[0.001579987,0.9965764,0.0002124025,0.0001286317,0.0001060012,0.000007775363,0.00004056708,0.000002210674,0.001346159],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003818339,"threshold_uncertainty_score":0.01277357,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02174568997137648,"score_gpt":0.2929579462296149,"score_spread":0.2712122562582384,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}