{"id":"W3157192435","doi":"10.3390/cells10050994","title":"Mechanosensitive Regulation of Fibrosis","year":2021,"lang":"en","type":"review","venue":"Cells","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Connaught Fund; University of Toronto","keywords":"Proinflammatory cytokine; Fibrosis; Inflammation; Context (archaeology); Mechanosensitive channels; Mechanobiology; Immune system; Cell biology; Mechanotransduction; Tissue remodeling; Neuroscience; Biology; Immunology; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000711039,0.0001690162,0.0005147082,0.0000510263,0.00002531751,0.00001078129,0.00009117877,0.0002832852,0.0001390774],"category_scores_gemma":[0.00002385029,0.0001607796,0.0004719197,0.0000999523,0.00001441368,0.000001108843,0.00009854533,0.00008944164,0.0000249654],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001465134,"about_ca_system_score_gemma":0.0001169869,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003967406,"about_ca_topic_score_gemma":0.000001986395,"domain_scores_codex":[0.9991636,0.00008104501,0.0002838697,0.0002901121,0.00007630932,0.0001050586],"domain_scores_gemma":[0.9992283,0.00001589895,0.0002286419,0.000377363,0.0001142717,0.00003552418],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000003630642,0.00006902318,1.917823e-8,0.002425272,0.000291185,0.000003339304,0.00001200091,0.000002457529,0.5035089,0.0006650042,0.008231457,0.4847877],"study_design_scores_gemma":[0.00002865286,0.00004261045,3.675683e-8,0.001181455,0.0001672127,0.000009517846,0.000007765506,0.000004577921,0.2294882,0.00001044164,0.7689441,0.000115415],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001295553,0.9970198,0.001179,0.000002337905,0.0004142326,0.0001762736,0.00008712083,0.000003385351,0.001104953],"genre_scores_gemma":[0.000099966,0.9945647,0.0003678527,0.00001060101,0.0001725689,0.00001206047,0.001316098,0.00003178074,0.003424396],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7607126,"threshold_uncertainty_score":0.6556402,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02174568997137648,"score_gpt":0.2929579462296149,"score_spread":0.2712122562582384,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}