{"id":"W3157248514","doi":"10.2215/cjn.16751020","title":"Effect of Apabetalone on Cardiovascular Events in Diabetes, CKD, and Recent Acute Coronary Syndrome","year":2021,"lang":"en","type":"article","venue":"Clinical Journal of the American Society of Nephrology","topic":"Protein Degradation and Inhibitors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"Resverlogix (Canada)","funders":"European Renal Association-European Dialysis and Transplant Association; American Society of Nephrology","keywords":"Medicine; Hazard ratio; Interquartile range; Internal medicine; Heart failure; Myocardial infarction; Acute coronary syndrome; Cardiology; Clinical endpoint; Adverse effect; Placebo; Diabetes mellitus; Confidence interval; Type 2 diabetes; Randomized controlled trial; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001198295,0.0001038045,0.0006648989,0.00001635634,0.00002107707,0.00000136496,0.0002072513,0.0001132818,0.000004584616],"category_scores_gemma":[0.000199824,0.00007294256,0.0008015109,0.000146844,0.0005990828,0.000003622566,0.0001673664,0.0002699934,3.91716e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000012516,"about_ca_system_score_gemma":0.00008812184,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003567078,"about_ca_topic_score_gemma":7.913604e-7,"domain_scores_codex":[0.9980421,0.0008884738,0.0005781946,0.0001720788,0.0001797815,0.0001393709],"domain_scores_gemma":[0.9987525,0.0001692289,0.0005985108,0.0003076723,0.0001098135,0.00006224912],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00171033,0.0006592313,0.4221588,0.00009726478,0.005699374,0.00004314704,0.000044591,0.0001184576,0.482393,0.000005516903,0.01079328,0.07627705],"study_design_scores_gemma":[0.004999385,0.01438598,0.7705121,0.0001368206,0.0005219487,0.0004677528,0.00007825869,0.00003582077,0.1768402,0.00009180709,0.03171666,0.0002132381],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960404,0.002274268,0.00002663561,0.001392824,0.0001547632,0.00009704839,0.000006437702,8.956478e-7,0.000006700773],"genre_scores_gemma":[0.9893976,0.00656338,0.0003832473,0.003555726,0.00006573728,0.000001891343,0.000005003655,0.000009164416,0.00001823411],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3483533,"threshold_uncertainty_score":0.2974511,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01214926710751583,"score_gpt":0.2964377649692089,"score_spread":0.284288497861693,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}