{"id":"W3157473730","doi":"10.3390/cancers13092208","title":"Novel Human Antibodies to Insulin Growth Factor 2 Receptor (IGF2R) for Radioimmunoimaging and Therapy of Canine and Human Osteosarcoma","year":2021,"lang":"en","type":"article","venue":"Cancers","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"University of Saskatchewan","keywords":"Antibody; Osteosarcoma; Radioimmunotherapy; Monoclonal antibody; In vivo; Cancer research; Targeted therapy; In vitro; Cancer; Chemistry; Medicine; Biology; Immunology; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002936793,0.0003920576,0.0001967472,0.0002902964,0.00008473368,0.000202195,0.0002786139,0.0003856961,0.0006872287],"category_scores_gemma":[0.0001455113,0.0001183323,0.000223877,0.0001456469,0.0001319,0.0001723856,0.0001732667,0.0004779347,0.0002142263],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003445671,"about_ca_system_score_gemma":0.0001525557,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004519208,"about_ca_topic_score_gemma":0.0008674556,"domain_scores_codex":[0.9998461,0.00003371033,0.000008071152,0.00003063512,0.00004373238,0.00003772028],"domain_scores_gemma":[0.9999527,0.00001008335,0.00001033922,0.000004515328,0.000009801016,0.00001253079],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000092895,0.0001224699,0.0004167738,0.00007350625,0.00001571825,0.00009251748,0.00002745845,0.0003637774,0.9858473,0.0002889836,0.0002820805,0.01237656],"study_design_scores_gemma":[0.00009495985,0.00293268,0.005112694,0.00002053094,0.00009018957,0.00211451,0.00002287782,0.003287913,0.9575194,0.0001271234,0.02865952,0.00001767908],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9241228,0.01520302,0.05250236,0.0003501134,0.0001577155,0.0003736764,0.0004046241,0.0004199091,0.006465813],"genre_scores_gemma":[0.9738868,0.00398038,0.01804577,0.0002526303,0.0000399128,0.00009877242,0.0008313293,0.00002606657,0.002838359],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006872287,"threshold_uncertainty_score":0.002500057,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05008577157426719,"score_gpt":0.3476195506148825,"score_spread":0.2975337790406153,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}