{"id":"W3157476749","doi":"10.1099/jgv.0.001588","title":"Induction of protective immune responses against a lethal Zika virus challenge post-vaccination with a dual serotype of recombinant vesicular stomatitis virus carrying the genetically modified Zika virus E protein gene","year":2021,"lang":"en","type":"article","venue":"Journal of General Virology","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Korea Centers for Disease Control and Prevention; Canadian Institutes of Health Research","keywords":"Virology; Vesicular stomatitis virus; Zika virus; Biology; Vaccination; Virus; Immune system; Flavivirus; Recombinant DNA; Attenuated vaccine; Gene; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000726084,0.000268498,0.0009014227,0.0002425488,0.0001256175,0.00001754781,0.0001740504,0.0002404792,0.00007244602],"category_scores_gemma":[0.0003801692,0.0001829393,0.0003056402,0.0002863122,0.0001359385,0.0001288985,0.00007703016,0.0005482521,0.000001461353],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001233388,"about_ca_system_score_gemma":0.0007366129,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003602252,"about_ca_topic_score_gemma":0.0001789221,"domain_scores_codex":[0.9969158,0.0008559254,0.001020746,0.0003095916,0.0005665346,0.0003314418],"domain_scores_gemma":[0.9968943,0.00008206894,0.001089919,0.0004187763,0.001372477,0.0001424458],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01230393,0.0007573943,0.0001171508,0.0001080054,0.000710586,0.0007199557,0.0005815083,0.0007030886,0.9677296,0.0002765953,0.00001281579,0.01597935],"study_design_scores_gemma":[0.008462373,0.01213192,0.1734939,0.000282505,0.0008140262,0.001924012,0.0004274846,0.001724022,0.7998221,0.0004757019,0.0001506202,0.0002913841],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892691,0.005354661,0.0008463003,0.00312587,0.0002541102,0.00104834,0.00003493514,0.00001137656,0.00005530597],"genre_scores_gemma":[0.9974914,0.0005580627,0.001125256,0.000262035,0.00033552,0.00009292734,0.00001496854,0.00004096851,0.00007889681],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1733767,"threshold_uncertainty_score":0.7460048,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01500273353446715,"score_gpt":0.2566780771894303,"score_spread":0.2416753436549631,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}