{"id":"W3157519920","doi":"10.1039/d1ob00524c","title":"An easily accessible, lower rim substituted calix[4]arene selectively binds <i>N</i>,<i>N</i>-dimethyllysine","year":2021,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Sulfonate; Methylation; Lysine; Stereochemistry; Calixarene; Arginine; Combinatorial chemistry; Molecule; Biochemistry; Amino acid; Organic chemistry; DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000981723,0.0002764279,0.0001491988,0.00008671686,0.0001183615,0.0001720614,0.0003113206,0.0002406844,0.001907627],"category_scores_gemma":[0.0001227788,0.0001235703,0.0001021901,0.0001063642,0.0001754919,0.0002407225,0.0001952198,0.0003825068,0.0003766425],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001909513,"about_ca_system_score_gemma":0.0001276632,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004233852,"about_ca_topic_score_gemma":0.00078305,"domain_scores_codex":[0.9999218,0.000008843506,0.000003004381,0.00002355196,0.00002074075,0.00002205108],"domain_scores_gemma":[0.9999256,0.00001565079,0.00002967812,0.000008818569,0.000008473717,0.00001180961],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000040797,0.00001169206,0.00005218409,0.00003935626,0.000002134493,0.00002392988,0.00001100573,0.00008273878,0.9986107,0.0001603737,0.00004353442,0.0009214413],"study_design_scores_gemma":[0.000007952031,0.0001968573,0.0005537292,0.000002288331,0.000003385971,0.00007416289,0.000009649231,0.000679129,0.9962851,0.00002061377,0.002161647,0.00000545413],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914734,0.0004546333,0.003298233,0.00005890154,0.00001808312,0.00002899436,0.0001172992,0.0001024826,0.004447986],"genre_scores_gemma":[0.991896,0.0004267094,0.003899878,0.00006535935,0.00001237508,0.00002718124,0.0001862053,0.00002103362,0.003465185],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001907627,"threshold_uncertainty_score":0.006381631,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0054385927468561,"score_gpt":0.2404763845815792,"score_spread":0.2350377918347231,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}