{"id":"W3157651421","doi":"10.1210/jendso/bvab048.336","title":"Results of the ADIUVO Study, the First Randomized Trial on Adjuvant Mitotane in Adrenocortical Carcinoma Patients","year":2021,"lang":"en","type":"article","venue":"Journal of the Endocrine Society","topic":"Adrenal and Paraganglionic Tumors","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Mitotane; Medicine; Adrenocortical carcinoma; Observational study; Adjuvant; Randomization; Clinical endpoint; Internal medicine; Randomized controlled trial; Stage (stratigraphy); Oncology; Surgery; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003977034,0.0008618031,0.002451634,0.0003335378,0.0004244502,0.001412857,0.0007196976,0.001132653,0.003465244],"category_scores_gemma":[0.008832214,0.0003607006,0.002601293,0.0004566342,0.0004225039,0.0005565128,0.0005942029,0.001208531,0.0002428019],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005841664,"about_ca_system_score_gemma":0.001082373,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001254583,"about_ca_topic_score_gemma":0.002326678,"domain_scores_codex":[0.9959618,0.002843839,0.0002734438,0.0004406328,0.0002674036,0.0002128777],"domain_scores_gemma":[0.9950518,0.002154712,0.001369412,0.000467319,0.0002752206,0.0006814642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.923866,0.001812002,0.02853459,0.002862625,0.008392055,0.00006407296,0.0001028314,0.0004421722,0.001397847,0.0004751431,0.002501874,0.02954878],"study_design_scores_gemma":[0.8363526,0.0452487,0.08811181,0.000812322,0.01819356,0.0001754454,0.0001148366,0.0008946973,0.0007300124,0.001016052,0.008277656,0.00007231887],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9280885,0.05128529,0.001000495,0.001516209,0.000980086,0.002451913,0.005298149,0.00006682265,0.009312372],"genre_scores_gemma":[0.9886351,0.003797817,0.0008135718,0.0008553462,0.0005251194,0.00138509,0.002544995,0.00001422843,0.001428635],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003977034,"threshold_uncertainty_score":0.02103281,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01498381762365383,"score_gpt":0.2708279553315681,"score_spread":0.2558441377079143,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}