{"id":"W3157746910","doi":"10.1210/jendso/bvab048.1449","title":"Design and Baseline Demographics of a Five-Year, Multi-National Observational Cohort Study of Children With Achondroplasia (ACHieve Study)","year":2021,"lang":"en","type":"article","venue":"Journal of the Endocrine Society","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Children's Hospital of Eastern Ontario","funders":"","keywords":"Achondroplasia; Medicine; Growth hormone receptor; Comorbidity; Internal medicine; Natriuretic peptide; Endochondral ossification; Fibroblast growth factor receptor 3; Pediatrics; Oncology; Bioinformatics; Biology; Growth hormone; Fibroblast growth factor; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001879504,0.0001366356,0.0004650548,0.00007955712,0.0001067586,0.00000936347,0.0001863617,0.00003457267,0.00003285362],"category_scores_gemma":[0.0009348898,0.0000856827,0.0001779706,0.0006167774,0.0001389573,0.0001002726,0.0001384937,0.0006481347,2.33836e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008468727,"about_ca_system_score_gemma":0.001247945,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002917844,"about_ca_topic_score_gemma":0.00002900172,"domain_scores_codex":[0.9967151,0.0004720357,0.0006771723,0.0001859041,0.001766849,0.0001829758],"domain_scores_gemma":[0.9964761,0.0005230496,0.000517197,0.0002424848,0.002097613,0.0001435421],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005814746,0.002701246,0.9925102,0.00008922934,0.001121958,0.00003492296,0.000608938,0.0006356437,0.0009127624,0.00001047489,0.0005556235,0.0002375091],"study_design_scores_gemma":[0.008533263,0.00202726,0.985204,0.00009192773,0.0002717216,0.0003792702,0.001879882,0.0008898171,0.0005717774,0.00001677067,0.00006995662,0.00006438859],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964405,0.0004984552,0.001020752,0.0008815602,0.00005598718,0.001074237,0.00001713725,0.000003822553,0.000007555152],"genre_scores_gemma":[0.9823455,0.0002109165,0.01685823,0.0002430956,0.00009688577,0.00001169458,0.000003867179,0.00002020195,0.0002096406],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01583748,"threshold_uncertainty_score":0.3494039,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07040401813909743,"score_gpt":0.3705737013547921,"score_spread":0.3001696832156947,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}