{"id":"W3157746910","doi":"10.1210/jendso/bvab048.1449","title":"Design and Baseline Demographics of a Five-Year, Multi-National Observational Cohort Study of Children With Achondroplasia (ACHieve Study)","year":2021,"lang":"en","type":"article","venue":"Journal of the Endocrine Society","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Children's Hospital of Eastern Ontario","funders":"","keywords":"Achondroplasia; Medicine; Growth hormone receptor; Comorbidity; Internal medicine; Natriuretic peptide; Endochondral ossification; Fibroblast growth factor receptor 3; Pediatrics; Oncology; Bioinformatics; Biology; Growth hormone; Fibroblast growth factor; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003135301,0.001093279,0.0009559782,0.001243244,0.00182626,0.001368207,0.001427672,0.001613369,0.003129323],"category_scores_gemma":[0.00218844,0.001246166,0.001469243,0.00171944,0.0006199114,0.001323637,0.001600653,0.00160274,0.000859599],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001044783,"about_ca_system_score_gemma":0.001027577,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01259539,"about_ca_topic_score_gemma":0.01527021,"domain_scores_codex":[0.9976329,0.0005859757,0.0002343173,0.0009164663,0.0003220659,0.0003083534],"domain_scores_gemma":[0.9985788,0.0001320827,0.0004802321,0.0002264048,0.0002734852,0.000309064],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008410584,0.0004019808,0.9968486,0.00004170689,0.0003054408,0.0001410483,0.0002146171,0.00005423338,0.0002578558,0.00006356127,0.0003845835,0.0004452325],"study_design_scores_gemma":[0.000353566,0.001265914,0.9957114,0.00003154855,0.0002326328,0.0003789421,0.0009039839,0.0002950704,0.00005871532,0.00007526654,0.0006709293,0.00002208306],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907548,0.0003037491,0.0005077811,0.00009051774,0.00002648858,0.0005678286,0.006945001,0.00001193875,0.0007919599],"genre_scores_gemma":[0.9886553,0.0001738934,0.0008790308,0.00028773,0.00003108587,0.001728208,0.007407295,0.00001423158,0.000823227],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01259539,"threshold_uncertainty_score":0.02504414,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07040401813909743,"score_gpt":0.3705737013547921,"score_spread":0.3001696832156947,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}