{"id":"W3157831860","doi":"","title":"Regulating gene expression through targeted RNA modification","year":2018,"lang":"en","type":"article","venue":"URSCA Proceedings","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Lethbridge","funders":"","keywords":"Pseudouridine; Biology; RNA; Guide RNA; Gene; Stop codon; Genetics; Uridine; Biochemistry; Genome; Genome editing","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001858385,0.0004010431,0.000269492,0.000211373,0.0001214402,0.0004266696,0.0003283632,0.000341672,0.0009639633],"category_scores_gemma":[0.0002118965,0.0001781675,0.0003685802,0.0001898649,0.0002773926,0.0001899489,0.0003194913,0.0005323389,0.0006392426],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003407151,"about_ca_system_score_gemma":0.0001561526,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000217323,"about_ca_topic_score_gemma":0.0003260573,"domain_scores_codex":[0.999685,0.00003538042,0.0000250101,0.0001170807,0.00008268424,0.00005476948],"domain_scores_gemma":[0.9998618,0.00003247277,0.00004514588,0.00002437671,0.00002143486,0.00001460773],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001432799,0.000006627984,0.00004883556,0.00003504863,0.000002697157,0.00002758365,0.00001110536,0.00006831831,0.997843,0.0002108205,0.00004235181,0.001689293],"study_design_scores_gemma":[0.000004377495,0.00005992295,0.0004047095,0.00000354976,0.000006599132,0.00007379651,0.000007079261,0.0005945311,0.9938272,0.0000512817,0.004962829,0.000004055365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8605655,0.005758502,0.1212206,0.0004867268,0.0004086592,0.000259978,0.001427491,0.002231397,0.007640994],"genre_scores_gemma":[0.9531552,0.003139912,0.034897,0.0002424295,0.00004915362,0.0002642358,0.001568296,0.0002233316,0.006460425],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009639633,"threshold_uncertainty_score":0.00322473,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02113120277152481,"score_gpt":0.2772696028929432,"score_spread":0.2561384001214184,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}