{"id":"W3157905541","doi":"10.1039/d1ce00337b","title":"Desolvation of dasatinib methanolate: an improved anhydrous polymorph","year":2021,"lang":"en","type":"article","venue":"CrystEngComm","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Mitacs","keywords":"Anhydrous; Dasatinib; Methanol; Transformation (genetics); Particle size; Particle (ecology); Chemistry; Materials science; Chemical engineering; Crystallography; Organic chemistry; Physical chemistry; Biology; Receptor; Biochemistry; Engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000906134,0.0001475692,0.0001485708,0.00008861207,0.0002607571,0.0002262335,0.0002105084,0.00028383,0.0024978],"category_scores_gemma":[0.000163538,0.00007776595,0.0001501138,0.0001574715,0.0002121799,0.0002826898,0.0002835396,0.0003297077,0.0005788118],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001698078,"about_ca_system_score_gemma":0.0001470685,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007929221,"about_ca_topic_score_gemma":0.001684381,"domain_scores_codex":[0.9999124,0.000007628933,0.000005089973,0.00001999412,0.00003915888,0.00001559322],"domain_scores_gemma":[0.9999633,0.00001102816,0.000006518384,0.000006440906,0.000007650224,0.00000508697],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002227184,0.00003737563,0.000268581,0.0001252595,0.000008043284,0.0005100346,0.0001166277,0.0004792104,0.9864295,0.00082886,0.001285043,0.009688817],"study_design_scores_gemma":[0.00002546505,0.0002181564,0.0007343252,0.000005965619,0.000009287898,0.0003568402,0.00008366255,0.001874889,0.9823183,0.0001509244,0.01421122,0.00001116857],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9721529,0.001412432,0.005612289,0.0006043855,0.0001091056,0.00006614273,0.0008614426,0.0003356171,0.01884575],"genre_scores_gemma":[0.9892598,0.0008489913,0.003714565,0.0001015743,0.00001754195,0.00002289225,0.0003695035,0.0001200249,0.005545025],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0024978,"threshold_uncertainty_score":0.008355975,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0204782935655088,"score_gpt":0.2628928317659162,"score_spread":0.2424145382004073,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}