{"id":"W3157905541","doi":"10.1039/d1ce00337b","title":"Desolvation of dasatinib methanolate: an improved anhydrous polymorph","year":2021,"lang":"en","type":"article","venue":"CrystEngComm","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Mitacs","keywords":"Anhydrous; Dasatinib; Methanol; Transformation (genetics); Particle size; Particle (ecology); Chemistry; Materials science; Chemical engineering; Crystallography; Organic chemistry; Physical chemistry; Biology; Receptor; Biochemistry; Engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001356275,0.0001290267,0.0002381353,0.00002990875,0.00009048109,0.00002848967,0.0002086886,0.0001216797,0.0007980646],"category_scores_gemma":[0.000130203,0.0001311077,0.00009053329,0.0001710573,0.00004536242,0.0001054804,0.00006002013,0.0001242442,0.00001410124],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002758466,"about_ca_system_score_gemma":0.00007942974,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007970854,"about_ca_topic_score_gemma":0.00003569292,"domain_scores_codex":[0.9990306,0.00003543614,0.0003496802,0.0002707053,0.0001292022,0.0001843176],"domain_scores_gemma":[0.9987253,0.0001300386,0.0001708703,0.0007374454,0.0001514058,0.00008495805],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000007703116,0.0001915662,0.0006552805,0.00006012247,0.00002695574,0.000002736698,0.0002288303,0.00000573318,0.9858564,0.001022872,0.00005351555,0.01188832],"study_design_scores_gemma":[0.0003815113,0.00001895432,0.0007563067,0.00005073841,0.00005182774,0.00002204827,0.0007317996,0.004866277,0.9888123,0.0005789832,0.003537418,0.0001918756],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9817437,0.0003090307,0.001100067,0.000209385,0.00003696815,0.00005567377,0.00004922675,0.00008774173,0.01640823],"genre_scores_gemma":[0.9941434,0.00001758273,0.004517067,0.00005363605,0.000117305,0.0000388583,0.0001174882,0.00002751344,0.0009671947],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01544103,"threshold_uncertainty_score":0.8738248,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0204782935655088,"score_gpt":0.2628928317659162,"score_spread":0.2424145382004073,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}