{"id":"W3157921908","doi":"10.1053/j.gastro.2021.04.067","title":"Results of the First Pilot Randomized Controlled Trial of Fecal Microbiota Transplant In Pediatric Ulcerative Colitis: Lessons, Limitations, and Future Prospects","year":2021,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; McMaster University; Population Health Research Institute","funders":"University of British Columbia; Université de Montréal; Canadian Institutes of Health Research; Hamilton Health Sciences","keywords":"Fecal bacteriotherapy; Ulcerative colitis; Medicine; Feces; Randomized controlled trial; Pilot trial; Internal medicine; Intensive care medicine; Biology; Microbiology; Antibiotics; Clostridium difficile; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007448941,0.0001728582,0.001417349,0.0001621912,0.00005031943,0.000008596217,0.0001029952,0.0001104584,0.0000158723],"category_scores_gemma":[0.0006448012,0.0001147437,0.0002803829,0.000255304,0.0002735972,0.00002628658,0.0000605784,0.0003422061,7.581633e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004570414,"about_ca_system_score_gemma":0.0002534929,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004142311,"about_ca_topic_score_gemma":0.001242619,"domain_scores_codex":[0.997483,0.0006943629,0.0009342862,0.000317029,0.0002473391,0.0003240044],"domain_scores_gemma":[0.99848,0.0006716421,0.0002748718,0.0002743921,0.0002267644,0.00007237171],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9893096,0.001067431,0.004690428,0.0001615267,0.0001899318,0.00005228134,0.0005187729,0.000003867151,0.003505041,0.0001886675,0.000243986,0.00006845604],"study_design_scores_gemma":[0.9432721,0.002209738,0.04911004,0.00008205467,0.0003664155,0.0001105106,0.0001794929,0.00003888005,0.004493814,0.00001865426,0.00006675467,0.00005158866],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9786369,0.0005159611,0.000005460919,0.01725938,0.0002680299,0.002925641,0.0001371509,0.000006936216,0.0002445075],"genre_scores_gemma":[0.9951751,0.003978048,0.00005860195,0.0001408783,0.0002926127,0.0001882379,0.00004221936,0.00001186634,0.000112466],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04603756,"threshold_uncertainty_score":0.4679114,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01970604837459784,"score_gpt":0.2676738862269131,"score_spread":0.2479678378523152,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}