{"id":"W3157921908","doi":"10.1053/j.gastro.2021.04.067","title":"Results of the First Pilot Randomized Controlled Trial of Fecal Microbiota Transplant In Pediatric Ulcerative Colitis: Lessons, Limitations, and Future Prospects","year":2021,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; McMaster University; Population Health Research Institute","funders":"University of British Columbia; Université de Montréal; Canadian Institutes of Health Research; Hamilton Health Sciences","keywords":"Fecal bacteriotherapy; Ulcerative colitis; Medicine; Feces; Randomized controlled trial; Pilot trial; Internal medicine; Intensive care medicine; Biology; Microbiology; Antibiotics; Clostridium difficile; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01343992,0.001600637,0.004685657,0.0003501499,0.0005656193,0.001865828,0.00096653,0.004063608,0.009028953],"category_scores_gemma":[0.02830503,0.0004445897,0.006210102,0.0007350423,0.001124746,0.002192223,0.0007070933,0.003427864,0.0008973167],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001195102,"about_ca_system_score_gemma":0.002252736,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00137245,"about_ca_topic_score_gemma":0.001937001,"domain_scores_codex":[0.9907166,0.006741496,0.0008601376,0.0006251067,0.000579779,0.0004768709],"domain_scores_gemma":[0.9799768,0.01273454,0.002742931,0.001895405,0.001340688,0.001309704],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8987308,0.003052051,0.004143705,0.00602496,0.01510782,0.000220178,0.0001213762,0.0004526382,0.001556204,0.0009473902,0.005796543,0.06384637],"study_design_scores_gemma":[0.8649582,0.08908094,0.01102477,0.001329095,0.02255929,0.0002202496,0.00009483674,0.000600555,0.0009810703,0.001557412,0.007536367,0.0000573273],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7238036,0.1613545,0.01472646,0.02826211,0.0154411,0.02789179,0.01145105,0.0008204126,0.01624896],"genre_scores_gemma":[0.9381163,0.0185918,0.009912489,0.0116128,0.003866098,0.01077004,0.002765151,0.00009711738,0.00426819],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01343992,"threshold_uncertainty_score":0.07107794,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01970604837459784,"score_gpt":0.2676738862269131,"score_spread":0.2479678378523152,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}