{"id":"W3158229865","doi":"10.1210/jendso/bvab048.1691","title":"Evaluation of the Optimal Thyroxine Levels for Thyroxine Hormone Replacement in Patients With Central Hypothyroidism","year":2021,"lang":"en","type":"article","venue":"Journal of the Endocrine Society","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Central hypothyroidism; Medicine; Hypopituitarism; Levothyroxine; Internal medicine; Reference range; Endocrinology; Waist; Anthropometry; Montreal Cognitive Assessment; Thyroid; Body mass index; Cognitive impairment","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008477826,0.0003124865,0.001034631,0.0001200684,0.0002207865,0.0003712863,0.000236635,0.0004077189,0.001248834],"category_scores_gemma":[0.0008127553,0.0001286603,0.000427292,0.0001665105,0.0002262591,0.000234447,0.0001586362,0.0006218606,0.0001624318],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002568316,"about_ca_system_score_gemma":0.000322474,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002434507,"about_ca_topic_score_gemma":0.0003681038,"domain_scores_codex":[0.9997403,0.0001221969,0.00003114205,0.00004212289,0.00003436659,0.00002995501],"domain_scores_gemma":[0.9994216,0.000203601,0.0001237051,0.00003441086,0.00004643594,0.0001702477],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.5996459,0.01282182,0.208614,0.001096721,0.001149917,0.0003554014,0.000446578,0.001338206,0.04712408,0.0001293673,0.0009115075,0.1263665],"study_design_scores_gemma":[0.07841478,0.5113291,0.3931987,0.0001421248,0.001107075,0.0009055297,0.0003073724,0.002977193,0.009643815,0.0002313453,0.001695985,0.00004686109],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980085,0.001386388,0.0001560903,0.00003922075,0.00001490048,0.00007855571,0.00004336157,0.000005655866,0.0002673727],"genre_scores_gemma":[0.9993712,0.0001402823,0.0002285442,0.00004531119,0.00001588735,0.00006589237,0.00004876327,8.695007e-7,0.00008321916],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001248834,"threshold_uncertainty_score":0.004483581,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02029085825076384,"score_gpt":0.2733518478887239,"score_spread":0.25306098963796,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}