{"id":"W3158356424","doi":"10.1016/j.clml.2021.04.013","title":"Sex Differences in Multiple Myeloma Biology but not Clinical Outcomes: Results from 3894 Patients in the Myeloma XI Trial","year":2021,"lang":"en","type":"article","venue":"Clinical Lymphoma Myeloma & Leukemia","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"Institute of Cancer Research; Cancer Research UK; Myeloma UK; National Cancer Research Institute; Celgene; University of Leeds; National Institute for Health and Care Research; Melanoma Research Alliance; Amgen; University of Birmingham; Cancer Research Institute","keywords":"Multiple myeloma; Dyscrasia; Lenalidomide; Incidence (geometry); Internal medicine; Disease; Cancer; Medicine; Oncology; Clinical trial; Plasma cell dyscrasia; Immunology; Plasma cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002520985,0.000442512,0.001385241,0.0001757952,0.0002860882,0.000851113,0.0005321776,0.0007322626,0.003379994],"category_scores_gemma":[0.003324611,0.0001947847,0.001397557,0.0005726975,0.0003201288,0.0004131127,0.0005250651,0.00110332,0.0003855926],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005699481,"about_ca_system_score_gemma":0.000532733,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009890962,"about_ca_topic_score_gemma":0.001589543,"domain_scores_codex":[0.998674,0.0007200862,0.0001112405,0.0001891194,0.0001629102,0.0001426811],"domain_scores_gemma":[0.9976041,0.0006450257,0.001064122,0.0002220351,0.0001036367,0.0003611886],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.6338851,0.002584549,0.2588991,0.001321505,0.01181748,0.0005002564,0.0004469584,0.001704129,0.003425247,0.0002954478,0.008240926,0.07687946],"study_design_scores_gemma":[0.1911941,0.06411151,0.7213749,0.0003401811,0.008741714,0.0008831792,0.0002591779,0.001133216,0.001081678,0.0006848268,0.01009692,0.00009857016],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903218,0.004997436,0.00008335186,0.0004394188,0.00003956395,0.0001946242,0.002630384,0.00001065618,0.001282784],"genre_scores_gemma":[0.9930999,0.001467992,0.0001939661,0.000547434,0.000103454,0.000338055,0.00297768,0.00001159333,0.001259793],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003379994,"threshold_uncertainty_score":0.01333237,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1172578914546457,"score_gpt":0.3878514811505375,"score_spread":0.2705935896958919,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}