{"id":"W3158403082","doi":"10.1016/j.jcyt.2021.02.008","title":"A PHASE I CLINICAL TRIAL ON INTRAVENOUS ADMINISTRATION OF IMMATURE HUMAN DENTAL PULP STEM CELLS (NESTACELL HDTM) TO HUNTINGTON'S DISEASE PATIENTS","year":2021,"lang":"en","type":"article","venue":"Cytotherapy","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canarie","funders":"","keywords":"Tolerability; Medicine; Huntington's disease; Adverse effect; Clinical trial; Disease; Internal medicine; Stem cell; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004628228,0.0008391333,0.001153653,0.0002836664,0.0003231243,0.0007107808,0.0005368095,0.001041598,0.004480227],"category_scores_gemma":[0.0003370081,0.0002196428,0.0006954303,0.0002520588,0.0007648464,0.0004271851,0.0001891333,0.00201827,0.0005896937],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004777368,"about_ca_system_score_gemma":0.0009493461,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001105433,"about_ca_topic_score_gemma":0.001875847,"domain_scores_codex":[0.9998847,0.00003447181,0.000003919618,0.00002814366,0.000008016744,0.00004069992],"domain_scores_gemma":[0.9998258,0.00003626104,0.00001978487,0.00001798922,0.00001154404,0.00008865731],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.568556,0.07895081,0.002313755,0.001446409,0.0008180419,0.0004377646,0.0004749314,0.003798613,0.1185101,0.001927913,0.008106505,0.2146592],"study_design_scores_gemma":[0.4469727,0.5300382,0.003204732,0.00008873243,0.000304554,0.0001879001,0.00009985852,0.001187841,0.01121815,0.0004799282,0.006188432,0.00002890559],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869965,0.002996033,0.001262022,0.0005745753,0.000346635,0.002857587,0.0009756361,0.0001289217,0.003862061],"genre_scores_gemma":[0.9861282,0.002647121,0.001652664,0.0006908232,0.0001408178,0.002565821,0.001309762,0.00002414215,0.00484072],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004480227,"threshold_uncertainty_score":0.01498783,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05740832628226835,"score_gpt":0.3648996748450458,"score_spread":0.3074913485627774,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}