{"id":"W3158487872","doi":"10.1371/journal.pone.0251172","title":"A biochemical mechanism for time-encoding memory formation within individual synapses of Purkinje cells","year":2021,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotchkiss Brain Institute; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; University of Calgary","keywords":"Purkinje cell; Neuroscience; Mechanism (biology); Metabotropic receptor; Metabotropic glutamate receptor; Stimulus (psychology); Stimulation; Cerebellum; Computer science; Biology; Glutamate receptor; Receptor; Physics; Psychology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002159888,0.0002936026,0.0003960942,0.000395141,0.0005007605,0.0006961026,0.001131026,0.0006990164,0.001013984],"category_scores_gemma":[0.0003879376,0.0002710241,0.0005176979,0.0001617169,0.0007464763,0.001427075,0.0005984865,0.0005776249,0.0004349459],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005317864,"about_ca_system_score_gemma":0.0003783985,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003221716,"about_ca_topic_score_gemma":0.0002418922,"domain_scores_codex":[0.9998341,0.00001289345,0.00001299495,0.00006177016,0.00004651739,0.00003171809],"domain_scores_gemma":[0.9997728,0.00002827601,0.00006566168,0.00005193979,0.00004178792,0.00003945775],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006905664,0.00005064878,0.0006998633,0.000188326,0.00003898888,0.0006781354,0.0001234341,0.003939892,0.9359301,0.04267573,0.0001784649,0.0154273],"study_design_scores_gemma":[0.00006669051,0.0005106271,0.004264984,0.00003507171,0.00009609883,0.001842444,0.0001374847,0.0650482,0.8921336,0.02940032,0.006377283,0.00008716251],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7057031,0.004948568,0.2784715,0.0009934858,0.0003211132,0.0001284037,0.0001623285,0.001637007,0.007634484],"genre_scores_gemma":[0.9664878,0.000967389,0.03009586,0.00006507884,0.00005218167,0.00008101285,0.00006929952,0.00002784151,0.002153509],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001131026,"threshold_uncertainty_score":0.003858447,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1202654022441311,"score_gpt":0.3082616237891527,"score_spread":0.1879962215450216,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}