{"id":"W3158528958","doi":"10.1007/s12029-021-00644-8","title":"Targeting the Mevalonate Pathway for Treating Esophageal Cancer","year":2021,"lang":"en","type":"review","venue":"Journal of Gastrointestinal Cancer","topic":"Cancer, Lipids, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Foothills Medical Centre; University of Calgary","funders":"","keywords":"Mevalonate pathway; Medicine; Esophageal cancer; Cancer; Malignancy; Radiation therapy; Cancer research; Bioinformatics; Oncology; Internal medicine; Biology; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004197045,0.000896287,0.001371459,0.00136483,0.0001763033,0.0007756419,0.000788074,0.0008614665,0.003297418],"category_scores_gemma":[0.0004108566,0.0002096663,0.0004859341,0.001181831,0.0003242645,0.0007459401,0.0005512347,0.002325386,0.001720227],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004543454,"about_ca_system_score_gemma":0.0006061064,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008891828,"about_ca_topic_score_gemma":0.002570022,"domain_scores_codex":[0.9999026,0.00001517057,0.00001165384,0.00001770648,0.00003909472,0.00001376413],"domain_scores_gemma":[0.9998674,0.0000504659,0.00002133116,0.000004010315,0.00003626442,0.00002055395],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001960921,0.0001117552,0.0001075838,0.0105188,0.0001542661,0.0001841575,0.00002312022,0.000444321,0.003816153,0.002150341,0.03792822,0.9443652],"study_design_scores_gemma":[0.0001167326,0.0002451052,0.0007823316,0.002105904,0.0002861209,0.001073153,0.00003266038,0.0002041938,0.001189876,0.001624061,0.9923143,0.00002556945],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001042607,0.9987816,0.0001444744,0.0002129659,0.0002232838,0.000004258178,0.00001922782,0.000009934118,0.0004999199],"genre_scores_gemma":[0.0007498825,0.9980082,0.0002286695,0.0002048866,0.0001568225,0.000006724747,0.00004091499,0.000001819275,0.0006021049],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003297418,"threshold_uncertainty_score":0.01103097,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03065367281705111,"score_gpt":0.3378637544945363,"score_spread":0.3072100816774852,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}