{"id":"W3158636166","doi":"10.1136/bmjdrc-2020-002091","title":"Glycation by glyoxal leads to profound changes in the behavior of dermal fibroblasts","year":2021,"lang":"en","type":"article","venue":"BMJ Open Diabetes Research & Care","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Université Laval","keywords":"Glycation; Fibroblast; Extracellular matrix; Wound healing; Glyoxal; Western blot; Chemistry; Elastin; Oil Red O; Diabetes mellitus; Internal medicine; Endocrinology; Medicine; Biochemistry; Cell biology; Biology; Immunology; Pathology; Adipose tissue","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001146259,0.0001159264,0.0001582117,0.00008347828,0.0001337118,0.00012983,0.0009766577,0.0000997868,0.00007788146],"category_scores_gemma":[0.001328047,0.00009847459,0.00003323094,0.000714884,0.0001372796,0.00001832969,0.0009909533,0.0002461979,0.00002207393],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005548687,"about_ca_system_score_gemma":0.0004468767,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004725973,"about_ca_topic_score_gemma":0.0007383625,"domain_scores_codex":[0.9973763,0.0006884942,0.0002086464,0.0005077742,0.00068871,0.0005300874],"domain_scores_gemma":[0.9978217,0.00009031812,0.00004599571,0.0008296678,0.001115026,0.00009730874],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007945153,0.0001146912,0.02427209,0.0001384641,0.00001132694,0.000007867709,0.0005082506,0.00003661877,0.9462876,0.00003949403,0.008349693,0.02015443],"study_design_scores_gemma":[0.0003343108,0.0004449939,0.01675014,0.00005854141,0.000003513388,0.000002938604,0.002130657,0.00000425848,0.9395792,0.00002176312,0.04053499,0.0001346672],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904315,0.001485375,0.0000102857,0.003324418,0.00003598506,0.003342154,0.00011644,0.000003175048,0.0012507],"genre_scores_gemma":[0.9929401,0.00009813133,0.0005814268,0.0002107506,0.0001301752,0.003339921,0.0007941051,0.00002441427,0.001880922],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0321853,"threshold_uncertainty_score":0.4015677,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.066103314813901,"score_gpt":0.4508366187632948,"score_spread":0.3847333039493938,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}