{"id":"W3158670300","doi":"10.3390/molecules26092690","title":"Design and Development of D‒α‒Tocopheryl Polyethylene Glycol Succinate‒block‒Poly(ε-Caprolactone) (TPGS−b−PCL) Nanocarriers for Solubilization and Controlled Release of Paclitaxel","year":2021,"lang":"en","type":"article","venue":"Molecules","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Nanocarriers; Copolymer; Micelle; Caprolactone; Polyethylene glycol; Dynamic light scattering; Chemistry; Dispersity; Polymerization; Solubility; Ethylene glycol; Polymer chemistry; Drug delivery; Nuclear chemistry; Aqueous solution; Materials science; Nanoparticle; Organic chemistry; Polymer; Nanotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006389113,0.0001940132,0.0004963165,0.00008138395,0.0001245749,0.00004028909,0.0001013277,0.00009341662,0.00003464879],"category_scores_gemma":[0.0005031679,0.0001827538,0.00005131687,0.0001505721,0.0001569547,0.0001207558,0.00008776795,0.00004158406,0.000002341795],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000427056,"about_ca_system_score_gemma":0.0004354162,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002520279,"about_ca_topic_score_gemma":0.00001719141,"domain_scores_codex":[0.998222,0.0002120167,0.0006107474,0.0003955886,0.0002626783,0.0002969785],"domain_scores_gemma":[0.9986165,0.0003951761,0.0002789305,0.0002489962,0.0003278358,0.0001325509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001457267,0.0001176733,0.0002042554,0.0002076933,0.00003771285,0.000009510441,0.0006835081,0.0002813436,0.9949809,0.0001702532,0.00003021973,0.001819619],"study_design_scores_gemma":[0.005659469,0.0001845637,0.0003020115,0.00007972849,0.00006330261,0.000006592726,0.0003815933,0.002712138,0.9901273,0.000253368,0.00004453854,0.0001853656],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9454728,0.002793613,0.05031229,0.0001156946,0.00007831985,0.001155641,0.00002935624,0.0000288328,0.00001339081],"genre_scores_gemma":[0.9447882,0.00003368667,0.05483364,0.00006776784,0.00001020288,0.0001847038,0.00000934345,0.00002565152,0.00004684485],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004853616,"threshold_uncertainty_score":0.7452482,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01597999513984081,"score_gpt":0.2374016301332781,"score_spread":0.2214216349934373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}