{"id":"W3158670300","doi":"10.3390/molecules26092690","title":"Design and Development of D‒α‒Tocopheryl Polyethylene Glycol Succinate‒block‒Poly(ε-Caprolactone) (TPGS−b−PCL) Nanocarriers for Solubilization and Controlled Release of Paclitaxel","year":2021,"lang":"en","type":"article","venue":"Molecules","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Nanocarriers; Copolymer; Micelle; Caprolactone; Polyethylene glycol; Dynamic light scattering; Chemistry; Dispersity; Polymerization; Solubility; Ethylene glycol; Polymer chemistry; Drug delivery; Nuclear chemistry; Aqueous solution; Materials science; Nanoparticle; Organic chemistry; Polymer; Nanotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002326757,0.0003646076,0.0002532938,0.0003251691,0.0001271995,0.0004052492,0.000309942,0.0002996689,0.0005725357],"category_scores_gemma":[0.0002097689,0.0002176878,0.0002578422,0.000171503,0.0001742256,0.000267166,0.00017607,0.0003028146,0.0004633805],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006532163,"about_ca_system_score_gemma":0.0005085856,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007379182,"about_ca_topic_score_gemma":0.00073857,"domain_scores_codex":[0.9998393,0.00001706368,0.00001847207,0.0000458732,0.00005187938,0.00002737841],"domain_scores_gemma":[0.9998738,0.00001143089,0.00005087105,0.00001000113,0.00002721238,0.00002670899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004595397,0.00003570996,0.0000787784,0.00003779505,0.000004692211,0.00002969151,0.000009464256,0.0006386464,0.9949156,0.0001540613,0.00002225001,0.00402726],"study_design_scores_gemma":[0.00003334238,0.0003002501,0.0003255425,0.000003364868,0.00001439644,0.00005824928,0.000004456042,0.00267222,0.9941876,0.00002685101,0.002369095,0.000004749317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9226166,0.003418612,0.06884878,0.0003108223,0.00008040843,0.0007121637,0.0003692585,0.0005222997,0.003121083],"genre_scores_gemma":[0.9250203,0.002320395,0.06591505,0.0001138726,0.00002255596,0.0003932303,0.0003887388,0.00006620802,0.005759515],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007379182,"threshold_uncertainty_score":0.004739463,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01597999513984081,"score_gpt":0.2374016301332781,"score_spread":0.2214216349934373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}