{"id":"W3158685006","doi":"10.1038/s41598-021-88516-w","title":"Chromatin occupancy and target genes of the haematopoietic master transcription factor MYB","year":2021,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute; University of British Columbia","funders":"Norges Forskningsråd; Universitetet i Oslo","keywords":"Chromatin; Transcription factor; MYB; Haematopoiesis; Occupancy; Gene; Biology; Genetics; Computational biology; Transcription (linguistics); Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006628163,0.000130132,0.0002040727,0.0002647041,0.0001303147,0.0002477652,0.00009628652,0.0001672902,0.001981712],"category_scores_gemma":[0.000126737,0.0001313637,0.0001453288,0.0002203782,0.0001320128,0.0001271459,0.0001815841,0.0001696631,0.0004984242],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001561044,"about_ca_system_score_gemma":0.00008517877,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001074779,"about_ca_topic_score_gemma":0.001130817,"domain_scores_codex":[0.999897,0.000005372289,0.000004440484,0.00005311014,0.00001721408,0.00002296026],"domain_scores_gemma":[0.9999232,0.00001480936,0.0000220298,0.000006466225,0.00001001413,0.00002345404],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000138816,0.000006948501,0.005559066,0.0000298009,0.000006205348,0.00001557924,0.0000331198,0.00006256419,0.993122,0.00004849838,0.00003292732,0.000944383],"study_design_scores_gemma":[0.00001269639,0.00009445281,0.606514,0.00001450325,0.00002024357,0.0002156009,0.0001352408,0.001063835,0.3898822,0.00009448436,0.001942675,0.00001001919],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995994,0.0009260069,0.0009344199,0.00002031528,0.000003260059,0.000003787379,0.001499559,0.00002288021,0.0005958254],"genre_scores_gemma":[0.9962416,0.0002195944,0.0006977553,0.00002691955,0.000002583243,0.00001055728,0.001569446,0.00001368122,0.001217925],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001981712,"threshold_uncertainty_score":0.006629467,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01017173230754336,"score_gpt":0.2123783106941537,"score_spread":0.2022065783866104,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}