{"id":"W3158723223","doi":"10.1099/mic.0.001047","title":"The ARC2 response in Streptomcyes coelicolor requires the global regulatory genes afsR and afsS","year":2021,"lang":"en","type":"article","venue":"Microbiology","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"MaRS; McMaster University; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Actinorhodin; Streptomyces coelicolor; Gene; Biology; Cell biology; Microbiology; Streptomyces; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001205494,0.0005755496,0.0003424057,0.0002730408,0.0001547172,0.0002892634,0.0001374761,0.0002004784,0.001026253],"category_scores_gemma":[0.0001292738,0.0001311861,0.0003146464,0.000198256,0.0002523325,0.0001246636,0.0002847524,0.0003891879,0.0003319849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003962062,"about_ca_system_score_gemma":0.0002254295,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002071728,"about_ca_topic_score_gemma":0.002339394,"domain_scores_codex":[0.9997217,0.00005447691,0.00002297888,0.00007380375,0.00006913229,0.0000579168],"domain_scores_gemma":[0.9998437,0.0000281613,0.00004135875,0.00002469694,0.00001887219,0.00004316112],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007376001,0.000009617435,0.00014767,0.0000147822,0.00000164446,0.00002405257,0.000008019155,0.00002836256,0.9993722,0.00001310296,0.000009063162,0.000297732],"study_design_scores_gemma":[0.00001047744,0.0002747157,0.01344181,0.000004027501,0.000008997491,0.0001628925,0.0000543296,0.0005031073,0.9845245,0.00002004685,0.0009889938,0.000006006564],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946172,0.000653545,0.002077097,0.00009548905,0.00001817346,0.00002513544,0.0007294971,0.0001365685,0.001647345],"genre_scores_gemma":[0.9937394,0.000277375,0.001870053,0.00006768587,0.000009350779,0.00003398821,0.001441174,0.0000411113,0.002519833],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002071728,"threshold_uncertainty_score":0.004119337,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01095418882009095,"score_gpt":0.2566540206023857,"score_spread":0.2456998317822948,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}