{"id":"W3158723223","doi":"10.1099/mic.0.001047","title":"The ARC2 response in Streptomcyes coelicolor requires the global regulatory genes afsR and afsS","year":2021,"lang":"en","type":"article","venue":"Microbiology","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"MaRS; McMaster University; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Actinorhodin; Streptomyces coelicolor; Gene; Biology; Cell biology; Microbiology; Streptomyces; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006463013,0.00013914,0.0002355545,0.00002435183,0.00017847,0.00002792379,0.0001335397,0.0001542236,0.00006065168],"category_scores_gemma":[0.0005461166,0.00006856243,0.00005944821,0.0001497674,0.0005310769,0.00002161161,0.0001685173,0.0001790143,0.00001502532],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007561818,"about_ca_system_score_gemma":0.0001536639,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003673459,"about_ca_topic_score_gemma":0.0004295483,"domain_scores_codex":[0.998624,0.0004487887,0.0002439297,0.0003432095,0.0000373338,0.0003027481],"domain_scores_gemma":[0.9990118,0.0003931056,0.00006173248,0.0004041893,0.00008671507,0.00004248763],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001423238,0.00003476511,0.005086733,0.0000150787,0.0000453823,0.00006358184,0.00007035561,2.711581e-7,0.9778464,0.0003623936,0.005526824,0.009524963],"study_design_scores_gemma":[0.0007259242,0.0002119943,0.1234492,0.00005846146,0.00004899531,0.00132009,0.000416523,0.000003122203,0.4225816,0.0002124865,0.4508198,0.0001517774],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9437304,0.01823365,6.447165e-7,0.037414,0.0002490331,0.0002145247,0.00003912926,0.00002140323,0.00009720615],"genre_scores_gemma":[0.9958606,0.0006981863,0.0001103827,0.001842489,0.0001466935,0.000002358239,0.00001585774,0.000008591764,0.001314847],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5552648,"threshold_uncertainty_score":0.2795895,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01095418882009095,"score_gpt":0.2566540206023857,"score_spread":0.2456998317822948,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}