{"id":"W3158848810","doi":"10.1158/1078-0432.ccr-20-4394","title":"Single-cell Profiles and Prognostic Impact of Tumor-Infiltrating Lymphocytes Coexpressing CD39, CD103, and PD-1 in Ovarian Cancer","year":2021,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":105,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; University of Victoria; Spinal Cord Injury BC; University of British Columbia","funders":"CIHR Skin Research Training Centre; BC Cancer Foundation; Terry Fox Research Institute; Canadian Cancer Society; Michael Smith Health Research BC; Paul G. Allen Frontiers Group; Canadian Institutes of Health Research; Cancer Research Society","keywords":"TIGIT; Biology; CD8; Tumor-infiltrating lymphocytes; Ovarian cancer; Immunology; Cancer research; Immune system; Immunotherapy; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009807995,0.00007614371,0.0001538257,0.0003303996,0.0001287692,0.0002674974,0.00006544529,0.0001766383,0.0007174244],"category_scores_gemma":[0.0002152392,0.00005982673,0.00006121019,0.000254567,0.0001054433,0.0001096622,0.0001103725,0.000123966,0.0001374618],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001295905,"about_ca_system_score_gemma":0.00007419635,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002898307,"about_ca_topic_score_gemma":0.0004002358,"domain_scores_codex":[0.9999359,0.00000824468,0.000005782056,0.00001635987,0.00001763511,0.00001598581],"domain_scores_gemma":[0.9998934,0.00002553735,0.00002610296,0.00001106424,0.00001827151,0.00002566709],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001617218,0.0001001433,0.2496073,0.00008136343,0.00002626783,0.0004902915,0.000227226,0.0002888227,0.7312531,0.00006581179,0.0001356664,0.01610686],"study_design_scores_gemma":[0.00004104167,0.001114004,0.8554914,0.0000149982,0.00008760626,0.003231991,0.000506957,0.003239178,0.1340571,0.0001209989,0.002084256,0.00001057122],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994916,0.0001593714,0.00009784802,0.000003468954,0.000001242241,0.000005030206,0.00006698522,0.000004988319,0.0001695516],"genre_scores_gemma":[0.9996276,0.00004346652,0.0001198771,0.000004708516,0.000001608394,0.000006363086,0.000101437,0.000001571239,0.00009347063],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007174244,"threshold_uncertainty_score":0.002400041,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1289289768247405,"score_gpt":0.4433742843298958,"score_spread":0.3144453075051553,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}