{"id":"W3158880088","doi":"10.4049/immunohorizons.2000040","title":"Tafazzin Modulates Allergen-Induced Mast Cell Inflammatory Mediator Secretion","year":2021,"lang":"en","type":"article","venue":"ImmunoHorizons","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Niagara Health System; Regional Municipality of Niagara; Brock University","funders":"Natural Sciences and Engineering Research Council of Canada; Brock University","keywords":"Degranulation; Small hairpin RNA; Mast cell; Immunoglobulin E; Cell biology; Immunology; Biology; Stem cell factor; Secretion; Gene knockdown; Chemistry; Molecular biology; Receptor; Endocrinology; Apoptosis; Biochemistry; Stem cell; Antibody","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001201089,0.0003153879,0.0002691726,0.0002217029,0.0001644269,0.0002739036,0.0001426447,0.0003117684,0.001582802],"category_scores_gemma":[0.00008276468,0.0001079077,0.0002534336,0.0001580692,0.0002200505,0.0001983078,0.0001750043,0.0007473945,0.000359011],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003023219,"about_ca_system_score_gemma":0.0001313413,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005294369,"about_ca_topic_score_gemma":0.0009606137,"domain_scores_codex":[0.999841,0.00001982675,0.0000169164,0.00003432406,0.00003503003,0.00005290804],"domain_scores_gemma":[0.999913,0.00001019151,0.00002765228,0.000006850304,0.00001178664,0.00003055792],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002077944,0.00002432587,0.0001676701,0.00003109869,0.000003023296,0.00001967928,0.0000057058,0.0000179306,0.9989961,0.00001759285,0.00003737959,0.0004717611],"study_design_scores_gemma":[0.00003883784,0.0004624239,0.01117443,0.000006798663,0.00002531844,0.0001033368,0.00004652215,0.0005620582,0.9856935,0.00002778701,0.001854479,0.000004486747],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995168,0.001922968,0.001102197,0.0001622921,0.00004446088,0.00003129058,0.0007609516,0.00006799496,0.0007399434],"genre_scores_gemma":[0.9952623,0.0008492627,0.0007979348,0.0000790989,0.00001561623,0.00004471936,0.0006632474,0.00001104587,0.002276633],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001582802,"threshold_uncertainty_score":0.005294979,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008181478022038653,"score_gpt":0.2058854485885537,"score_spread":0.1977039705665151,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}