{"id":"W3158886261","doi":"10.1007/978-1-0716-1311-5_19","title":"Transduction of Human T Cell Subsets with Lentivirus","year":2021,"lang":"en","type":"book-chapter","venue":"Methods in molecular biology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"","keywords":"Transduction (biophysics); Lentivirus; CD8; Chimeric antigen receptor; Cytotoxic T cell; Biology; T cell; Transgene; Gene; Molecular biology; Cell biology; Antigen; Virology; Immunology; Genetics; Human immunodeficiency virus (HIV); Immune system; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001931542,0.0005064805,0.0002410849,0.000253429,0.0001474343,0.0007227465,0.0003659502,0.0002136925,0.004000305],"category_scores_gemma":[0.00008499369,0.0001905815,0.0003292905,0.0002167068,0.0001753238,0.0003647091,0.0003059203,0.0008873576,0.001771451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00023389,"about_ca_system_score_gemma":0.0001775375,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003687448,"about_ca_topic_score_gemma":0.0003903807,"domain_scores_codex":[0.9999164,0.000009517469,0.000006259401,0.00001545873,0.0000340504,0.00001821704],"domain_scores_gemma":[0.9999725,0.00001021867,0.000003049858,0.000006209694,0.000004492279,0.000003476861],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005428405,0.00003427079,0.00006497477,0.0001050414,0.00000642827,0.00009071494,0.00005493645,0.00023379,0.9498019,0.005846034,0.002008261,0.04169929],"study_design_scores_gemma":[0.00002423411,0.0001697534,0.0004513743,0.00003210269,0.00002106191,0.0004759445,0.00002437076,0.001134649,0.8680624,0.001991638,0.1276041,0.000008351477],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.2444924,0.03582821,0.4368753,0.001063391,0.001956244,0.0008693061,0.004632538,0.003898344,0.2703842],"genre_scores_gemma":[0.5037633,0.03184119,0.09886868,0.001053446,0.0003401743,0.0008432726,0.006816365,0.001004235,0.3554693],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.004000305,"threshold_uncertainty_score":0.01338238,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05896044766884998,"score_gpt":0.4231030252602356,"score_spread":0.3641425775913856,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}