{"id":"W3158914167","doi":"10.15252/embr.202050958","title":"Chromatin remodeller CHD7 is required for GABAergic neuron development by promoting PAQR3 expression","year":2021,"lang":"en","type":"article","venue":"EMBO Reports","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Université du Québec à Montréal; Centre Hospitalier de l’Université de Montréal; Institut National de la Recherche Scientifique","funders":"CHARGE Syndrome Foundation; Fonds de Recherche du Québec - Santé; Canada Foundation for Innovation; Natural Sciences and Engineering Research Council of Canada; Government of Canada; Canadian Institutes of Health Research; Rare Disease Foundation","keywords":"Chromatin; GABAergic; Neuron; Cell biology; Biology; Over expression; Neuroscience; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001611876,0.0003893789,0.0002697938,0.0003335286,0.0003722894,0.0006844844,0.0005946564,0.0005326305,0.005467335],"category_scores_gemma":[0.0002777785,0.0004081462,0.0003443363,0.0001316445,0.0004855854,0.0003661631,0.0007398298,0.001256109,0.002157565],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005388884,"about_ca_system_score_gemma":0.0004514087,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001678615,"about_ca_topic_score_gemma":0.004954407,"domain_scores_codex":[0.9997242,0.000016522,0.00001600091,0.00007836417,0.00008861542,0.00007620085],"domain_scores_gemma":[0.9996939,0.0000402904,0.0000844356,0.00003259091,0.00003621196,0.0001125902],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007759569,0.000006127664,0.0004695205,0.00002585158,0.000005220407,0.0001136894,0.000008481674,0.00002836585,0.9980223,0.0002235153,0.0001389515,0.0008804033],"study_design_scores_gemma":[0.00002039511,0.00002942949,0.01436257,0.000007143118,0.00001422,0.0002808357,0.00005227305,0.0009564817,0.9798779,0.0001119397,0.004279185,0.000007613961],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9713476,0.002290844,0.01691973,0.0005642872,0.0002249826,0.0000388412,0.002046411,0.0009324744,0.005634889],"genre_scores_gemma":[0.9875631,0.0003477238,0.00286064,0.000121083,0.00001554822,0.00002381598,0.001775226,0.0002367076,0.007056179],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005467335,"threshold_uncertainty_score":0.01829004,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01329502305716961,"score_gpt":0.2718308297389408,"score_spread":0.2585358066817712,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}