{"id":"W3158914167","doi":"10.15252/embr.202050958","title":"Chromatin remodeller CHD7 is required for GABAergic neuron development by promoting PAQR3 expression","year":2021,"lang":"en","type":"article","venue":"EMBO Reports","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Université du Québec à Montréal; Centre Hospitalier de l’Université de Montréal; Institut National de la Recherche Scientifique","funders":"CHARGE Syndrome Foundation; Fonds de Recherche du Québec - Santé; Canada Foundation for Innovation; Natural Sciences and Engineering Research Council of Canada; Government of Canada; Canadian Institutes of Health Research; Rare Disease Foundation","keywords":"Chromatin; GABAergic; Neuron; Cell biology; Biology; Over expression; Neuroscience; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003222678,0.0001843787,0.0002018341,0.00002353393,0.0001586133,0.00003172634,0.00006316161,0.0001619091,0.000007377161],"category_scores_gemma":[0.0001916992,0.0001637507,0.0001248643,0.00008860173,0.00002878451,0.000005774083,0.0001226281,0.00006395927,8.606636e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002091971,"about_ca_system_score_gemma":0.0001087798,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001631758,"about_ca_topic_score_gemma":0.00000295477,"domain_scores_codex":[0.9983901,0.00005026184,0.0004781454,0.0006499955,0.0001731844,0.0002583141],"domain_scores_gemma":[0.9989689,0.00000893711,0.000295491,0.0004759143,0.0001725624,0.00007821032],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000117484,0.0000596862,0.0001091707,0.00002950776,0.0000254753,0.00005237312,0.0000608214,0.000002253494,0.9763229,4.967622e-7,0.0169522,0.006373354],"study_design_scores_gemma":[0.0001056404,0.00005219236,0.00004194876,0.00006100323,0.00001485052,0.0001509993,0.00002291229,0.0001411303,0.8908461,0.0000761558,0.1082842,0.0002027931],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9848039,0.0005975452,0.01308155,0.0003130749,0.0001129051,0.0002761459,0.000008267578,0.00007883827,0.0007277483],"genre_scores_gemma":[0.9558824,0.00006349215,0.03874523,0.0003567169,0.0001158078,0.00003394888,0.0005283798,0.0000333518,0.00424067],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09133202,"threshold_uncertainty_score":0.667756,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01329502305716961,"score_gpt":0.2718308297389408,"score_spread":0.2585358066817712,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}